Molecular Mechanism for the Role of the H2A and H2B Histone Tails in Nucleosome Repositioning

The nucleosome core particle (NCP) is the basic packaging unit of DNA. Recently reported structures of the NCP suggest that the histone octamer undergoes conformational changes during the process of DNA translocation around the histone octamer. Herein, we demonstrate with long-time all-atomistic mol...

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Veröffentlicht in:	The journal of physical chemistry. B 2018-12, Vol.122 (50), p.11827-11840
Hauptverfasser:	Chakraborty, Kaushik, Kang, Myungshim, Loverde, Sharon M
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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