Trial of personalised care after treatment—Prostate cancer: A randomised feasibility trial of a nurse‐led psycho‐educational intervention
Objective The present parallel randomised control trial evaluated the feasibility of a nurse‐led psycho‐educational intervention aimed at improving the self‐management of prostate cancer survivors. Methods We identified 305 eligible patients from a district general hospital, diagnosed 9–48 months pr...
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| Veröffentlicht in: | European journal of cancer care 2019-03, Vol.28 (2), p.e12966-n/a |
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| container_title | European journal of cancer care |
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| creator | Stanciu, Marian Andrei Morris, Caroline Makin, Matt Watson, Eila Bulger, Jenna Evans, Richard Hiscock, Julia Hoare, Zoë Edwards, Rhiannon Tudor Neal, Richard D. Yeo, Seow Tien Wilkinson, Clare |
| description | Objective
The present parallel randomised control trial evaluated the feasibility of a nurse‐led psycho‐educational intervention aimed at improving the self‐management of prostate cancer survivors.
Methods
We identified 305 eligible patients from a district general hospital, diagnosed 9–48 months previously, who completed radical treatment, or were monitored clinically (ineligible for treatment). Ninety‐five patients were recruited by blinded selection and randomised to Intervention (N = 48) and Control (N = 47) groups. Participant allocation was revealed to patients and researchers after recruitment was completed. For 36 weeks, participants received augmented usual care (Control) or augmented usual care and additional nurse support (Intervention) provided in two community hospitals and a university clinic, or by telephone.
Results
Data from 91 participants (Intervention, N = 45; Control, N = 46) were analysed. All feasibility metrics met predefined targets: recruitment rate (31.15%; 95% CI: 25.95%–36.35%), attrition rate (9.47%; 95% CI: 3.58%–15.36%) and outcome measures completion rates (77%–92%). Forty‐five patients received the intervention, with no adverse events. The Extended Prostate Cancer Index Composite can inform the minimum sample size for a future effectiveness trial. The net intervention cost was £317 per patient.
Conclusions
The results supported the feasibility and acceptability of the intervention, suggesting that it should be evaluated in a fully powered trial to assess its effectiveness and cost‐effectiveness. |
| doi_str_mv | 10.1111/ecc.12966 |
| format | Article |
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The present parallel randomised control trial evaluated the feasibility of a nurse‐led psycho‐educational intervention aimed at improving the self‐management of prostate cancer survivors.
Methods
We identified 305 eligible patients from a district general hospital, diagnosed 9–48 months previously, who completed radical treatment, or were monitored clinically (ineligible for treatment). Ninety‐five patients were recruited by blinded selection and randomised to Intervention (N = 48) and Control (N = 47) groups. Participant allocation was revealed to patients and researchers after recruitment was completed. For 36 weeks, participants received augmented usual care (Control) or augmented usual care and additional nurse support (Intervention) provided in two community hospitals and a university clinic, or by telephone.
Results
Data from 91 participants (Intervention, N = 45; Control, N = 46) were analysed. All feasibility metrics met predefined targets: recruitment rate (31.15%; 95% CI: 25.95%–36.35%), attrition rate (9.47%; 95% CI: 3.58%–15.36%) and outcome measures completion rates (77%–92%). Forty‐five patients received the intervention, with no adverse events. The Extended Prostate Cancer Index Composite can inform the minimum sample size for a future effectiveness trial. The net intervention cost was £317 per patient.
Conclusions
The results supported the feasibility and acceptability of the intervention, suggesting that it should be evaluated in a fully powered trial to assess its effectiveness and cost‐effectiveness.</description><identifier>ISSN: 0961-5423</identifier><identifier>EISSN: 1365-2354</identifier><identifier>DOI: 10.1111/ecc.12966</identifier><identifier>PMID: 30478975</identifier><language>eng</language><publisher>England: Hindawi Limited</publisher><subject>Aged ; Aged, 80 and over ; Cancer ; Cancer Survivors - psychology ; Cost-Benefit Analysis ; Delivery of Health Care - economics ; Delivery of Health Care - methods ; Disease management ; Education ; Evidence-based medicine ; Feasibility Studies ; general practice ; Humans ; Identification methods ; Intervention ; Male ; Middle Aged ; needs assessment ; nurse practitioners ; Nurse specialists ; Nursing care ; Patient assessment ; patient care ; Patient education ; Patient Education as Topic - economics ; Patient Education as Topic - methods ; Patient Satisfaction ; Patients ; Precision Medicine - economics ; Precision Medicine - nursing ; Precision Medicine - psychology ; Prostate cancer ; Prostatic Neoplasms - economics ; Prostatic Neoplasms - nursing ; Prostatic Neoplasms - psychology ; Psychotherapy ; Psychotherapy - economics ; Psychotherapy - methods ; Quality-Adjusted Life Years ; Randomization ; Recruitment ; Surveys and Questionnaires ; Survivor ; Treatment Outcome ; urology</subject><ispartof>European journal of cancer care, 2019-03, Vol.28 (2), p.e12966-n/a</ispartof><rights>2018 John Wiley & Sons Ltd</rights><rights>2018 John Wiley & Sons Ltd.</rights><rights>Copyright © 2019 John Wiley & Sons Ltd</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3886-ace2a1504a19c80eff139a571c65c8f5545b2d0aa083b0e9cb3c65c8a6babede3</citedby><cites>FETCH-LOGICAL-c3886-ace2a1504a19c80eff139a571c65c8f5545b2d0aa083b0e9cb3c65c8a6babede3</cites><orcidid>0000-0001-7492-1898</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fecc.12966$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fecc.12966$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30478975$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Stanciu, Marian Andrei</creatorcontrib><creatorcontrib>Morris, Caroline</creatorcontrib><creatorcontrib>Makin, Matt</creatorcontrib><creatorcontrib>Watson, Eila</creatorcontrib><creatorcontrib>Bulger, Jenna</creatorcontrib><creatorcontrib>Evans, Richard</creatorcontrib><creatorcontrib>Hiscock, Julia</creatorcontrib><creatorcontrib>Hoare, Zoë</creatorcontrib><creatorcontrib>Edwards, Rhiannon Tudor</creatorcontrib><creatorcontrib>Neal, Richard D.</creatorcontrib><creatorcontrib>Yeo, Seow Tien</creatorcontrib><creatorcontrib>Wilkinson, Clare</creatorcontrib><title>Trial of personalised care after treatment—Prostate cancer: A randomised feasibility trial of a nurse‐led psycho‐educational intervention</title><title>European journal of cancer care</title><addtitle>Eur J Cancer Care (Engl)</addtitle><description>Objective
The present parallel randomised control trial evaluated the feasibility of a nurse‐led psycho‐educational intervention aimed at improving the self‐management of prostate cancer survivors.
Methods
We identified 305 eligible patients from a district general hospital, diagnosed 9–48 months previously, who completed radical treatment, or were monitored clinically (ineligible for treatment). Ninety‐five patients were recruited by blinded selection and randomised to Intervention (N = 48) and Control (N = 47) groups. Participant allocation was revealed to patients and researchers after recruitment was completed. For 36 weeks, participants received augmented usual care (Control) or augmented usual care and additional nurse support (Intervention) provided in two community hospitals and a university clinic, or by telephone.
Results
Data from 91 participants (Intervention, N = 45; Control, N = 46) were analysed. All feasibility metrics met predefined targets: recruitment rate (31.15%; 95% CI: 25.95%–36.35%), attrition rate (9.47%; 95% CI: 3.58%–15.36%) and outcome measures completion rates (77%–92%). Forty‐five patients received the intervention, with no adverse events. The Extended Prostate Cancer Index Composite can inform the minimum sample size for a future effectiveness trial. The net intervention cost was £317 per patient.
Conclusions
The results supported the feasibility and acceptability of the intervention, suggesting that it should be evaluated in a fully powered trial to assess its effectiveness and cost‐effectiveness.</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Cancer</subject><subject>Cancer Survivors - psychology</subject><subject>Cost-Benefit Analysis</subject><subject>Delivery of Health Care - economics</subject><subject>Delivery of Health Care - methods</subject><subject>Disease management</subject><subject>Education</subject><subject>Evidence-based medicine</subject><subject>Feasibility Studies</subject><subject>general practice</subject><subject>Humans</subject><subject>Identification methods</subject><subject>Intervention</subject><subject>Male</subject><subject>Middle Aged</subject><subject>needs assessment</subject><subject>nurse practitioners</subject><subject>Nurse specialists</subject><subject>Nursing care</subject><subject>Patient assessment</subject><subject>patient care</subject><subject>Patient education</subject><subject>Patient Education as Topic - economics</subject><subject>Patient Education as Topic - methods</subject><subject>Patient Satisfaction</subject><subject>Patients</subject><subject>Precision Medicine - economics</subject><subject>Precision Medicine - nursing</subject><subject>Precision Medicine - psychology</subject><subject>Prostate cancer</subject><subject>Prostatic Neoplasms - economics</subject><subject>Prostatic Neoplasms - nursing</subject><subject>Prostatic Neoplasms - psychology</subject><subject>Psychotherapy</subject><subject>Psychotherapy - economics</subject><subject>Psychotherapy - methods</subject><subject>Quality-Adjusted Life Years</subject><subject>Randomization</subject><subject>Recruitment</subject><subject>Surveys and Questionnaires</subject><subject>Survivor</subject><subject>Treatment Outcome</subject><subject>urology</subject><issn>0961-5423</issn><issn>1365-2354</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kctOwzAQRS0EouWx4AeQJTawSGvHcR7sqoqXVAkWZR1NnIlwlSbFdkDd8Qew4Av5EtwHLJDwxhrNmXvHvoSccDbg_gxRqQEPszjeIX0uYhmEQka7pM-ymAcyCkWPHFg7Y4wLnkX7pCdYlKRZIvvkfWo01LSt6AKNbRuotcWSKjBIoXJoqDMIbo6N-3r7fDCtdeDQ9xuF5pKOqIGmbOfroQrB6kLX2i391FYWaNMZi19vH7VHFnapnlpfYNkpcHplSHXjfV68gy-PyF4FtcXj7X1IHq-vpuPbYHJ_czceTQIl0jQOQGEIXLIIeKZShlXFRQYy4SqWKq2kjGQRlgyApaJgmKlCrDsQF1BgieKQnG90F6Z97tC63L9BYV1Dg21n85CLNI5YmCQePfuDztrO-MVXVMYSIaVYURcbSvk_sgarfGH0HMwy5yxfpZT7lPJ1Sp493Sp2xRzLX_InFg8MN8CrrnH5v1J-NR5vJL8BtSehsg</recordid><startdate>201903</startdate><enddate>201903</enddate><creator>Stanciu, Marian Andrei</creator><creator>Morris, Caroline</creator><creator>Makin, Matt</creator><creator>Watson, Eila</creator><creator>Bulger, Jenna</creator><creator>Evans, Richard</creator><creator>Hiscock, Julia</creator><creator>Hoare, Zoë</creator><creator>Edwards, Rhiannon Tudor</creator><creator>Neal, Richard D.</creator><creator>Yeo, Seow Tien</creator><creator>Wilkinson, Clare</creator><general>Hindawi Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>8FD</scope><scope>ASE</scope><scope>FPQ</scope><scope>FR3</scope><scope>K6X</scope><scope>K9.</scope><scope>M7Z</scope><scope>NAPCQ</scope><scope>P64</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-7492-1898</orcidid></search><sort><creationdate>201903</creationdate><title>Trial of personalised care after treatment—Prostate cancer: A randomised feasibility trial of a nurse‐led psycho‐educational intervention</title><author>Stanciu, Marian Andrei ; Morris, Caroline ; Makin, Matt ; Watson, Eila ; Bulger, Jenna ; Evans, Richard ; Hiscock, Julia ; Hoare, Zoë ; Edwards, Rhiannon Tudor ; Neal, Richard D. ; Yeo, Seow Tien ; Wilkinson, Clare</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3886-ace2a1504a19c80eff139a571c65c8f5545b2d0aa083b0e9cb3c65c8a6babede3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Cancer</topic><topic>Cancer Survivors - psychology</topic><topic>Cost-Benefit Analysis</topic><topic>Delivery of Health Care - economics</topic><topic>Delivery of Health Care - methods</topic><topic>Disease management</topic><topic>Education</topic><topic>Evidence-based medicine</topic><topic>Feasibility Studies</topic><topic>general practice</topic><topic>Humans</topic><topic>Identification methods</topic><topic>Intervention</topic><topic>Male</topic><topic>Middle Aged</topic><topic>needs assessment</topic><topic>nurse practitioners</topic><topic>Nurse specialists</topic><topic>Nursing care</topic><topic>Patient assessment</topic><topic>patient care</topic><topic>Patient education</topic><topic>Patient Education as Topic - economics</topic><topic>Patient Education as Topic - methods</topic><topic>Patient Satisfaction</topic><topic>Patients</topic><topic>Precision Medicine - economics</topic><topic>Precision Medicine - nursing</topic><topic>Precision Medicine - psychology</topic><topic>Prostate cancer</topic><topic>Prostatic Neoplasms - economics</topic><topic>Prostatic Neoplasms - nursing</topic><topic>Prostatic Neoplasms - psychology</topic><topic>Psychotherapy</topic><topic>Psychotherapy - economics</topic><topic>Psychotherapy - methods</topic><topic>Quality-Adjusted Life Years</topic><topic>Randomization</topic><topic>Recruitment</topic><topic>Surveys and Questionnaires</topic><topic>Survivor</topic><topic>Treatment Outcome</topic><topic>urology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Stanciu, Marian Andrei</creatorcontrib><creatorcontrib>Morris, Caroline</creatorcontrib><creatorcontrib>Makin, Matt</creatorcontrib><creatorcontrib>Watson, Eila</creatorcontrib><creatorcontrib>Bulger, Jenna</creatorcontrib><creatorcontrib>Evans, Richard</creatorcontrib><creatorcontrib>Hiscock, Julia</creatorcontrib><creatorcontrib>Hoare, Zoë</creatorcontrib><creatorcontrib>Edwards, Rhiannon Tudor</creatorcontrib><creatorcontrib>Neal, Richard D.</creatorcontrib><creatorcontrib>Yeo, Seow Tien</creatorcontrib><creatorcontrib>Wilkinson, Clare</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Technology Research Database</collection><collection>British Nursing Index</collection><collection>British Nursing Index (BNI) (1985 to Present)</collection><collection>Engineering Research Database</collection><collection>British Nursing Index</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biochemistry Abstracts 1</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>European journal of cancer care</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Stanciu, Marian Andrei</au><au>Morris, Caroline</au><au>Makin, Matt</au><au>Watson, Eila</au><au>Bulger, Jenna</au><au>Evans, Richard</au><au>Hiscock, Julia</au><au>Hoare, Zoë</au><au>Edwards, Rhiannon Tudor</au><au>Neal, Richard D.</au><au>Yeo, Seow Tien</au><au>Wilkinson, Clare</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Trial of personalised care after treatment—Prostate cancer: A randomised feasibility trial of a nurse‐led psycho‐educational intervention</atitle><jtitle>European journal of cancer care</jtitle><addtitle>Eur J Cancer Care (Engl)</addtitle><date>2019-03</date><risdate>2019</risdate><volume>28</volume><issue>2</issue><spage>e12966</spage><epage>n/a</epage><pages>e12966-n/a</pages><issn>0961-5423</issn><eissn>1365-2354</eissn><abstract>Objective
The present parallel randomised control trial evaluated the feasibility of a nurse‐led psycho‐educational intervention aimed at improving the self‐management of prostate cancer survivors.
Methods
We identified 305 eligible patients from a district general hospital, diagnosed 9–48 months previously, who completed radical treatment, or were monitored clinically (ineligible for treatment). Ninety‐five patients were recruited by blinded selection and randomised to Intervention (N = 48) and Control (N = 47) groups. Participant allocation was revealed to patients and researchers after recruitment was completed. For 36 weeks, participants received augmented usual care (Control) or augmented usual care and additional nurse support (Intervention) provided in two community hospitals and a university clinic, or by telephone.
Results
Data from 91 participants (Intervention, N = 45; Control, N = 46) were analysed. All feasibility metrics met predefined targets: recruitment rate (31.15%; 95% CI: 25.95%–36.35%), attrition rate (9.47%; 95% CI: 3.58%–15.36%) and outcome measures completion rates (77%–92%). Forty‐five patients received the intervention, with no adverse events. The Extended Prostate Cancer Index Composite can inform the minimum sample size for a future effectiveness trial. The net intervention cost was £317 per patient.
Conclusions
The results supported the feasibility and acceptability of the intervention, suggesting that it should be evaluated in a fully powered trial to assess its effectiveness and cost‐effectiveness.</abstract><cop>England</cop><pub>Hindawi Limited</pub><pmid>30478975</pmid><doi>10.1111/ecc.12966</doi><tpages>11</tpages><orcidid>https://orcid.org/0000-0001-7492-1898</orcidid><oa>free_for_read</oa></addata></record> |
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| ispartof | European journal of cancer care, 2019-03, Vol.28 (2), p.e12966-n/a |
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| subjects | Aged Aged, 80 and over Cancer Cancer Survivors - psychology Cost-Benefit Analysis Delivery of Health Care - economics Delivery of Health Care - methods Disease management Education Evidence-based medicine Feasibility Studies general practice Humans Identification methods Intervention Male Middle Aged needs assessment nurse practitioners Nurse specialists Nursing care Patient assessment patient care Patient education Patient Education as Topic - economics Patient Education as Topic - methods Patient Satisfaction Patients Precision Medicine - economics Precision Medicine - nursing Precision Medicine - psychology Prostate cancer Prostatic Neoplasms - economics Prostatic Neoplasms - nursing Prostatic Neoplasms - psychology Psychotherapy Psychotherapy - economics Psychotherapy - methods Quality-Adjusted Life Years Randomization Recruitment Surveys and Questionnaires Survivor Treatment Outcome urology |
| title | Trial of personalised care after treatment—Prostate cancer: A randomised feasibility trial of a nurse‐led psycho‐educational intervention |
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