Genetic Association between Alzheimer’s Disease Risk Variant of the PICALM Gene and Auditory Event-Related Potentials in Aging

Aging and genetic predisposition are major risk factors in age-related neurodegenerative disorders. The most common neurodegenerative disorder is Alzheimer’s disease (AD). Genome-wide association studies (GWAS) have identified statistically significant association of the PICALM rs3851179 polymorphis...

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Veröffentlicht in:	Biochemistry (Moscow) 2018-09, Vol.83 (9), p.1075-1082
Hauptverfasser:	Ponomareva, N. V., Andreeva, T. V., Protasova, M. A., Filippova, Yu. V., Kolesnikova, E. P., Fokin, V. F., Illarioshkin, S. N., Rogaev, E. I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age Aged Aging Aging (Biology) Aging - genetics Alleles Alzheimer Disease - genetics Alzheimer Disease - pathology Alzheimer's disease Auditory evoked potentials Biochemistry Biomedical and Life Sciences Biomedicine Bioorganic Chemistry Cognitive ability Cortex Data processing Event-related potentials Evoked Potentials - physiology Female Gene polymorphism Genetic aspects Genetic polymorphisms Genetic Predisposition to Disease Genome-wide association studies Genomes Genotype Genotypes Health aspects Health risks Humans Information processing Latency Life Sciences Male Microbiology Middle Aged Monomeric Clathrin Assembly Proteins - genetics Neural networks Neurodegeneration Neurodegenerative diseases Polymorphism Polymorphism, Single Nucleotide Risk analysis Risk Factors Statistical analysis Statistical significance Young Adult
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