Stopped-Flow Kinetic Techniques for Studying Binding Reactions of Intrinsically Disordered Proteins

Intrinsically disordered proteins are abundant in signaling processes such as transcription. Suitable binding and unbinding rates of proteins with their partners are critical for allowing them to perform their biological roles. Understanding how these are achieved, and indeed designing strategies fo...

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Veröffentlicht in:	Methods in enzymology 2018, Vol.611, p.423-457
Hauptverfasser:	Crabtree, Michael D, Shammas, Sarah L
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Animals Equipment Design Humans Intrinsically Disordered Proteins - chemistry Intrinsically Disordered Proteins - metabolism Kinetics Protein Binding Protein Conformation Protein Folding Spectrometry, Fluorescence - instrumentation Spectrometry, Fluorescence - methods Static Electricity
Online-Zugang:	Volltext
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