Dynamic MCP-1 mRNA response of human aortic endothelial cells (HAEC) to step changes in laminar shear stress

Our aim is to study the hemodynamic alteration of monocyte recruitment and adhesion in model blood vessel systems, focusing on the hemodynamic effects of the recruitment factor monocyte chemotactic protein one, MCP-1, gene expression in HAEC. Preconditioning with low shear stress, LS, elevates MCP-1...

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Bibliographische Detailangaben

Hauptverfasser:	Guild, J.B., Chromiak, A.B., Sprague, E.A., Nerem, R.M.
Format:	Tagungsbericht
Sprache:	eng
Schlagworte:	Biomedical engineering Blood vessels Cell culture Cells Chemical technology Gene expression Genetic engineering Hemodynamics Humans In vivo Recruitment RNA Shear stress Stress Switches
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