Epigenetics of the molecular clock and bacterial diversity in bipolar disorder

•Methylation of the clock gene ARNTL (cg05733463) correlated negatively with bacterial diversity and evenness in Bipolar Disorder. Objectives The gut microbiome harbors substantially more genetic material than our body cells and has an impact on a huge variety of physiological mechanisms including t...

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Veröffentlicht in:	Psychoneuroendocrinology 2019-03, Vol.101, p.160-166
Hauptverfasser:	Bengesser, S.A., Mörkl, S., Painold, A., Dalkner, N., Birner, A., Fellendorf, F.T., Platzer, M., Queissner, R., Hamm, C., Maget, A., Pilz, R., Rieger, A., Wagner-Skacel, J., Reininghaus, B., Kapfhammer, H.P., Petek, E., Kashofer, K., Halwachs, B., Holzer, P., Waha, A., Reininghaus, E.Z.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult ARNTL ARNTL Transcription Factors - genetics ARNTL Transcription Factors - metabolism Bipolar disorder Bipolar Disorder - genetics Bipolar Disorder - microbiology Bipolar Disorder - physiopathology Circadian Rhythm - genetics Circadian Rhythm - physiology Depression - genetics Depressive Disorder - genetics DNA Methylation Epigenesis, Genetic - genetics Epigenetics Epigenomics - methods Female Gastrointestinal Microbiome - genetics Gastrointestinal Microbiome - physiology Gut microbiome Humans Male Microbiota - genetics Middle Aged Pilot Projects RNA, Ribosomal, 16S - genetics
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