Plate‐shape carbonated hydroxyapatite/collagen nanocomposite hydrogel via in situ mineralization of hydroxyapatite concurrent with gelation of collagen at pH = 7.4 and 37°C

ABSTRACT The objective of this study was to develop a collagen/hydroxyapatite (HA) nanocomposite scaffold for bone tissue engineering applications. For this purpose, in situ mineralization of HA was accompanied with formation of collagen hydrogel at condition similar to the physiological condition,...

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Veröffentlicht in:	Journal of biomedical materials research. Part B, Applied biomaterials Applied biomaterials, 2019-08, Vol.107 (6), p.1920-1929
Hauptverfasser:	Takallu, Sara, Mirzaei, Esmaeil, Azadi, Amir, Karimizade, Ayoob, Tavakol, Shima
Format:	Artikel
Sprache:	eng
Schlagworte:	Biocompatibility Biological properties Biomedical materials Carbonation Collagen Fabrication Gelation hydrogel Hydrogels Hydroxyapatite in situ mineralization Materials research Materials science Mineralization Morphology nanocomposite Nanocomposites Osteogenesis pH effects Plates (structural members) Powder Scaffolds Scanning electron microscopy Spherical powders Surgical implants Tissue engineering X-ray diffraction
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