A Targeting Nanotherapy for Abdominal Aortic Aneurysms

Abdominal aortic aneurysm (AAA) is a leading cause of mortality and morbidity in the elderly. Currently, there remain no effective drugs that can prevent the growth of aneurysms and delay aneurysm rupture in the clinical setting. The aim of this study was to develop a nanotherapy that can target ane...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of the American College of Cardiology 2018-11, Vol.72 (21), p.2591-2605
Hauptverfasser:	Cheng, Juan, Zhang, Runjun, Li, Chenwen, Tao, Hui, Dou, Yin, Wang, Yuquan, Hu, Houyuan, Zhang, Jianxiang
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdomen aneurysm Aneurysms Animals Aortic Aneurysm, Abdominal - drug therapy Aortic Aneurysm, Abdominal - metabolism Aortic Aneurysm, Abdominal - pathology Aortic aneurysms Apoptosis Biomimetics Calcification Cardiology Cell adhesion & migration Cell membranes Cells, Cultured Clinical trials Coronary vessels Drug Delivery Systems - methods Drug development Drugs Efficiency Experiments Flow cytometry Geriatrics Immunosuppressive Agents - administration & dosage In vivo methods and tests Inflammation Laboratory animals Ligands Macrophages Male Mice Morbidity Mortality Muscle, Smooth, Vascular - drug effects Muscle, Smooth, Vascular - metabolism Muscle, Smooth, Vascular - pathology Myocytes, Smooth Muscle - drug effects Myocytes, Smooth Muscle - metabolism Myocytes, Smooth Muscle - pathology Nanoparticles Nanoparticles - administration & dosage nanotherapy Older people Oxidative stress Peptides Random Allocation Rapamycin Rats Rats, Sprague-Dawley RAW 264.7 Cells Reactive oxygen species Reactive Oxygen Species - antagonists & inhibitors Reactive Oxygen Species - metabolism Rodents Sirolimus - administration & dosage Statistical analysis targeting Vascular diseases
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!