Glomerular basement membrane duplication is a predictor of the prognosis of diabetic nephropathy in patients with type 2 diabetes

Background Several clinical parameters and pathological findings are known to be predictors of the deterioration of diabetic nephropathy (DN). Glomerular basement membrane duplication (GBM-DP) is a pathological feature representing endothelial injury, which is commonly observed in DN. In the present...

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Veröffentlicht in:	Clinical and experimental nephrology 2019-04, Vol.23 (4), p.521-529
Hauptverfasser:	Yamakawa, Takafumi, Kawaguchi, Takehiko, Kitamura, Hiroshi, Kadomura, Moritoshi, Nishimura, Motonobu, Yokoo, Takashi, Imasawa, Toshiyuki
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Atrophy - pathology Basement membranes Biopsy Blood pressure Diabetes Diabetes mellitus Diabetes mellitus (non-insulin dependent) Diabetes Mellitus, Type 2 - complications Diabetic Nephropathies - complications Diabetic Nephropathies - pathology Diabetic Nephropathies - physiopathology Diabetic nephropathy Disease Progression End-stage renal disease Epidermal growth factor receptors Excretion Female Fibrosis Glomerular Basement Membrane - pathology Glomerular Filtration Rate Glomerulus Humans Kaplan-Meier Estimate Kidney diseases Kidney Failure, Chronic - etiology Kidney Failure, Chronic - physiopathology Kidney Tubules - pathology Male Medicine Medicine & Public Health Middle Aged Nephrology Nephropathy Original Article Prognosis Proportional Hazards Models Regression analysis Risk Factors Urology
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