Changes in body composition during adjuvant chemotherapy for breast cancer
The In Vivo Neutron Capture Analysis (IVNCA) technique was used to investigate the changes in body composition of patients with breast cancer receiving adjuvant CMF (cyclophosphamide, methotrexate, 5-fluorouracil) chemotherapy, and to determine if cumulative protein catabolism was a sequela of such...
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| Veröffentlicht in: | Applied radiation and isotopes 1998-05, Vol.49 (5), p.637-638 |
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| container_title | Applied radiation and isotopes |
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| creator | Aslani, Alireza Smith, Ross C. Allen, Barry J. Levi, John A. |
| description | The In Vivo Neutron Capture Analysis (IVNCA) technique was used to investigate the changes in body composition of patients with breast cancer receiving adjuvant CMF (cyclophosphamide, methotrexate, 5-fluorouracil) chemotherapy, and to determine if cumulative protein catabolism was a sequela of such therapy. The body composition was determined by measurements of: TBN (total body nitrogen) and body fat. The total body water (TBW) (+bone) was calculated by difference in a four compartmental model. Results show that the weight gain during adjuvant CMF chemotherapy is due to a gain in TBW and TBF. Furthermore, the TBN was found to be constant, indicating the absence of cumulative cancer cachexia and protein catabolism arising from the chemotherapy. |
| doi_str_mv | 10.1016/S0969-8043(97)00199-1 |
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The body composition was determined by measurements of: TBN (total body nitrogen) and body fat. The total body water (TBW) (+bone) was calculated by difference in a four compartmental model. Results show that the weight gain during adjuvant CMF chemotherapy is due to a gain in TBW and TBF. 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The body composition was determined by measurements of: TBN (total body nitrogen) and body fat. The total body water (TBW) (+bone) was calculated by difference in a four compartmental model. Results show that the weight gain during adjuvant CMF chemotherapy is due to a gain in TBW and TBF. 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| ispartof | Applied radiation and isotopes, 1998-05, Vol.49 (5), p.637-638 |
| issn | 0969-8043 1872-9800 |
| language | eng |
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| source | MEDLINE; Access via ScienceDirect (Elsevier) |
| subjects | Adult Aged Analysis of Variance Anthropometry - methods Antineoplastic Combined Chemotherapy Protocols - therapeutic use Body Composition - drug effects Body Composition - physiology Body fluids Body Weight Breast Neoplasms - drug therapy Breast Neoplasms - physiopathology Breast Neoplasms - surgery Chemotherapy, Adjuvant Cyclophosphamide Female Fluorouracil Humans Methotrexate Middle Aged Nitrogen - analysis Oncology Proteins Proteins - analysis Radiotherapy |
| title | Changes in body composition during adjuvant chemotherapy for breast cancer |
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