Bandgap Engineered Polypyrrole–Polydopamine Hybrid with Intrinsic Raman and Photoacoustic Imaging Contrasts
Intrinsically multimodal nanomaterials have revealed their great potential as a new class of contrast agents. We herein report a bandgap engineering strategy to develop an intrinsically Raman-photoacoustic (PA) active probe that is based on semiconducting conjugated polymers. This dual modal probe i...
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| Veröffentlicht in: | Nano letters 2018-12, Vol.18 (12), p.7485-7493 |
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| container_end_page | 7493 |
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| container_issue | 12 |
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| container_title | Nano letters |
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| creator | Lin, Qinrui Yang, Yuhong Ma, Yanyun Zhang, Ren Wang, Jiucun Chen, Xin Shao, Zhengzhong |
| description | Intrinsically multimodal nanomaterials have revealed their great potential as a new class of contrast agents. We herein report a bandgap engineering strategy to develop an intrinsically Raman-photoacoustic (PA) active probe that is based on semiconducting conjugated polymers. This dual modal probe is prepared by doping a semiconducting conjugated polymer with polydopamine (PDA) through a one-pot reaction. When applied in the polypyrrole (PPy), this strategy can enhance Raman scattering and the PA amplitude of PPy–PDA hybrid by 3.2 and 2.4 times, respectively, so that both signals can be further applied in bioimaging. In the hybrid, such a dual-enhancement effect is achieved by infusing these two macromolecules at the nanoscale to reduce the optical bandgap energy. This work not only introduces a dual modal contrast agent but also provides a new method of manipulating semiconducting polymer’s inherent optical features for bioimaging. |
| doi_str_mv | 10.1021/acs.nanolett.8b02901 |
| format | Article |
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We herein report a bandgap engineering strategy to develop an intrinsically Raman-photoacoustic (PA) active probe that is based on semiconducting conjugated polymers. This dual modal probe is prepared by doping a semiconducting conjugated polymer with polydopamine (PDA) through a one-pot reaction. When applied in the polypyrrole (PPy), this strategy can enhance Raman scattering and the PA amplitude of PPy–PDA hybrid by 3.2 and 2.4 times, respectively, so that both signals can be further applied in bioimaging. In the hybrid, such a dual-enhancement effect is achieved by infusing these two macromolecules at the nanoscale to reduce the optical bandgap energy. 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We herein report a bandgap engineering strategy to develop an intrinsically Raman-photoacoustic (PA) active probe that is based on semiconducting conjugated polymers. This dual modal probe is prepared by doping a semiconducting conjugated polymer with polydopamine (PDA) through a one-pot reaction. When applied in the polypyrrole (PPy), this strategy can enhance Raman scattering and the PA amplitude of PPy–PDA hybrid by 3.2 and 2.4 times, respectively, so that both signals can be further applied in bioimaging. In the hybrid, such a dual-enhancement effect is achieved by infusing these two macromolecules at the nanoscale to reduce the optical bandgap energy. 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| ispartof | Nano letters, 2018-12, Vol.18 (12), p.7485-7493 |
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| source | MEDLINE; American Chemical Society Journals |
| subjects | Animals Contrast Media - chemistry Electron Transport HeLa Cells Humans Indoles - chemistry Mice Nanoparticles - chemistry Photoacoustic Techniques - methods Polymers - chemistry Pyrroles - chemistry Semiconductors Spectrum Analysis, Raman - methods |
| title | Bandgap Engineered Polypyrrole–Polydopamine Hybrid with Intrinsic Raman and Photoacoustic Imaging Contrasts |
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