Cognitive performance and its relationship with postprandial metabolic changes after ingestion of different macronutrients in the morning
The effect of carbohydrate, protein and fat ingestion on simple as well as complex cognitive functions and the relationship between the respective postprandial metabolic changes and changes in cognitive performance were studied in fifteen healthy male students. Subjects were tested in three sessions...
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| Veröffentlicht in: | British journal of nutrition 2001-03, Vol.85 (3), p.393-405 |
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| creator | Fischer, Karina Colombani, Paolo C. Langhans, Wolfgang Wenk, Caspar |
| description | The effect of carbohydrate, protein and fat ingestion on simple as well as complex cognitive functions and the relationship between the respective postprandial metabolic changes and changes in cognitive performance were studied in fifteen healthy male students. Subjects were tested in three sessions, separated by 1 week, for short-term changes in blood variables, indirect calorimetry, subjective performance and different objective performance tasks using a repeated-measures counterbalanced cross-over design. Measurements were made after an overnight fast before and hourly during 3 h after test meal ingestion. Test meals consisted of either pure carbohydrates, protein or fat and were served as isoenergetic (1670 kJ) spoonable creams with similar sensory properties. Most aspects of subjective performance did not differ between test meals. For all objective tasks, however, postprandial cognitive performance was best after fat ingestion concomitant with an almost constant glucose metabolism and constant metabolic activation state measured by glucagon:insulin (G:I). In contrast, carbohydrate as well as protein ingestion resulted in lower overall cognitive performance, both together with partly marked changes (P |
| doi_str_mv | 10.1079/BJN2000269 |
| format | Article |
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Subjects were tested in three sessions, separated by 1 week, for short-term changes in blood variables, indirect calorimetry, subjective performance and different objective performance tasks using a repeated-measures counterbalanced cross-over design. Measurements were made after an overnight fast before and hourly during 3 h after test meal ingestion. Test meals consisted of either pure carbohydrates, protein or fat and were served as isoenergetic (1670 kJ) spoonable creams with similar sensory properties. Most aspects of subjective performance did not differ between test meals. For all objective tasks, however, postprandial cognitive performance was best after fat ingestion concomitant with an almost constant glucose metabolism and constant metabolic activation state measured by glucagon:insulin (G:I). In contrast, carbohydrate as well as protein ingestion resulted in lower overall cognitive performance, both together with partly marked changes (P<0.001) in glucose metabolism and metabolic activation. They also differently affected specific cognitive functions (P<0.05) in relation to their specific effect on metabolism. Carbohydrate ingestion resulted in relatively better short-term memory and accuracy of tasks concomitant with low metabolic activation, whereas protein ingestion resulted in better attention and efficiency of tasks concomitant with higher metabolic activation. Our findings support the concept that good and stable cognitive performance is related to a balanced glucose metabolism and metabolic activation state.</description><identifier>ISSN: 0007-1145</identifier><identifier>EISSN: 1475-2662</identifier><identifier>DOI: 10.1079/BJN2000269</identifier><identifier>PMID: 11299085</identifier><identifier>CODEN: BJNUAV</identifier><language>eng</language><publisher>Cambridge, UK: Cambridge University Press</publisher><subject>Adult ; Biological and medical sciences ; Blood Glucose - metabolism ; Calorimetry ; Calorimetry, Indirect ; Carbohydrates ; Cognition & reasoning ; Cognition - drug effects ; Cognitive ability ; Cognitive performance ; Cross-Over Studies ; Diet - psychology ; Dietary Carbohydrates - pharmacology ; Dietary Fats - pharmacology ; Dietary Proteins - pharmacology ; Energy Metabolism - physiology ; Feeding. Feeding behavior ; Fundamental and applied biological sciences. Psychology ; Glucagon ; Glucagon - blood ; Glucose ; Hormones - blood ; Humans ; Ingestion ; Insulin - blood ; Macronutrient ingestion ; Male ; Meals ; Memory - drug effects ; Metabolism ; Metabolites ; Nutrition ; Postprandial metabolism ; Postprandial Period - physiology ; Proteins ; Reaction Time - drug effects ; Respiratory Mechanics - physiology ; Surveys and Questionnaires ; Vertebrates: anatomy and physiology, studies on body, several organs or systems</subject><ispartof>British journal of nutrition, 2001-03, Vol.85 (3), p.393-405</ispartof><rights>Copyright © The Nutrition Society 2001</rights><rights>2001 INIST-CNRS</rights><rights>The Nutrition Society</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c490t-772ff8e46b439fea83a5fe591313b150f03d7f469d10c97ea8741baeb26f2c803</citedby><cites>FETCH-LOGICAL-c490t-772ff8e46b439fea83a5fe591313b150f03d7f469d10c97ea8741baeb26f2c803</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=941509$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11299085$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Fischer, Karina</creatorcontrib><creatorcontrib>Colombani, Paolo C.</creatorcontrib><creatorcontrib>Langhans, Wolfgang</creatorcontrib><creatorcontrib>Wenk, Caspar</creatorcontrib><title>Cognitive performance and its relationship with postprandial metabolic changes after ingestion of different macronutrients in the morning</title><title>British journal of nutrition</title><addtitle>Br J Nutr</addtitle><description>The effect of carbohydrate, protein and fat ingestion on simple as well as complex cognitive functions and the relationship between the respective postprandial metabolic changes and changes in cognitive performance were studied in fifteen healthy male students. Subjects were tested in three sessions, separated by 1 week, for short-term changes in blood variables, indirect calorimetry, subjective performance and different objective performance tasks using a repeated-measures counterbalanced cross-over design. Measurements were made after an overnight fast before and hourly during 3 h after test meal ingestion. Test meals consisted of either pure carbohydrates, protein or fat and were served as isoenergetic (1670 kJ) spoonable creams with similar sensory properties. Most aspects of subjective performance did not differ between test meals. For all objective tasks, however, postprandial cognitive performance was best after fat ingestion concomitant with an almost constant glucose metabolism and constant metabolic activation state measured by glucagon:insulin (G:I). In contrast, carbohydrate as well as protein ingestion resulted in lower overall cognitive performance, both together with partly marked changes (P<0.001) in glucose metabolism and metabolic activation. They also differently affected specific cognitive functions (P<0.05) in relation to their specific effect on metabolism. Carbohydrate ingestion resulted in relatively better short-term memory and accuracy of tasks concomitant with low metabolic activation, whereas protein ingestion resulted in better attention and efficiency of tasks concomitant with higher metabolic activation. Our findings support the concept that good and stable cognitive performance is related to a balanced glucose metabolism and metabolic activation state.</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Blood Glucose - metabolism</subject><subject>Calorimetry</subject><subject>Calorimetry, Indirect</subject><subject>Carbohydrates</subject><subject>Cognition & reasoning</subject><subject>Cognition - drug effects</subject><subject>Cognitive ability</subject><subject>Cognitive performance</subject><subject>Cross-Over Studies</subject><subject>Diet - psychology</subject><subject>Dietary Carbohydrates - pharmacology</subject><subject>Dietary Fats - pharmacology</subject><subject>Dietary Proteins - pharmacology</subject><subject>Energy Metabolism - physiology</subject><subject>Feeding. Feeding behavior</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Glucagon</subject><subject>Glucagon - blood</subject><subject>Glucose</subject><subject>Hormones - blood</subject><subject>Humans</subject><subject>Ingestion</subject><subject>Insulin - blood</subject><subject>Macronutrient ingestion</subject><subject>Male</subject><subject>Meals</subject><subject>Memory - drug effects</subject><subject>Metabolism</subject><subject>Metabolites</subject><subject>Nutrition</subject><subject>Postprandial metabolism</subject><subject>Postprandial Period - physiology</subject><subject>Proteins</subject><subject>Reaction Time - drug effects</subject><subject>Respiratory Mechanics - physiology</subject><subject>Surveys and Questionnaires</subject><subject>Vertebrates: anatomy and physiology, studies on body, several organs or systems</subject><issn>0007-1145</issn><issn>1475-2662</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNptkctu1TAQhi0EoofChgdAFkgsEAFfkjhe0qO2XCoQEmzYWI4zPscliVPb4fIIvDWOTtQjIVb2zHzz658ZhB5T8ooSIV-fvf_ICCGslnfQhpaiKlhds7tok5OioLSsTtCDGK9z2FAi76MTSpmUpKk26M_W70aX3A_AEwTrw6BHA1iPHXYp4gC9Ts6Pce8m_NOlPZ58TFPIdad7PEDSre-dwWavxx1ErG2CgN3yX_qwt7hz1kKAMeFBm-DHOQWXo5gpnPaABx_G3PAQ3bO6j_BofU_R14vzL9u3xdWny3fbN1eFKSVJhRDM2gbKui25tKAbrisLlaSc8pZWxBLeCVvWsqPESJEBUdJWQ8tqy0xD-Cl6ftCdgr-Zs001uGig7_UIfo6KUV7mPdUZfPoPeO3nMGZvC9PwikqeoRcHKE8WYwCrpuAGHX4rStRyHXW8ToafrIpzO0B3RNdzZODZCuhodG_zno2Lt5ws84CLTHGgXEzw67aqw3dVCy4qVV9-VvwbKxk7k-pD5l-uHvXQBtft4DjJf1z-BXv3tcA</recordid><startdate>20010301</startdate><enddate>20010301</enddate><creator>Fischer, Karina</creator><creator>Colombani, Paolo C.</creator><creator>Langhans, Wolfgang</creator><creator>Wenk, Caspar</creator><general>Cambridge University Press</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7RV</scope><scope>7T5</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>AN0</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>M0K</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7TK</scope></search><sort><creationdate>20010301</creationdate><title>Cognitive performance and its relationship with postprandial metabolic changes after ingestion of different macronutrients in the morning</title><author>Fischer, Karina ; Colombani, Paolo C. ; Langhans, Wolfgang ; Wenk, Caspar</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c490t-772ff8e46b439fea83a5fe591313b150f03d7f469d10c97ea8741baeb26f2c803</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Blood Glucose - metabolism</topic><topic>Calorimetry</topic><topic>Calorimetry, Indirect</topic><topic>Carbohydrates</topic><topic>Cognition & reasoning</topic><topic>Cognition - drug effects</topic><topic>Cognitive ability</topic><topic>Cognitive performance</topic><topic>Cross-Over Studies</topic><topic>Diet - psychology</topic><topic>Dietary Carbohydrates - pharmacology</topic><topic>Dietary Fats - pharmacology</topic><topic>Dietary Proteins - pharmacology</topic><topic>Energy Metabolism - physiology</topic><topic>Feeding. Feeding behavior</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Glucagon</topic><topic>Glucagon - blood</topic><topic>Glucose</topic><topic>Hormones - blood</topic><topic>Humans</topic><topic>Ingestion</topic><topic>Insulin - blood</topic><topic>Macronutrient ingestion</topic><topic>Male</topic><topic>Meals</topic><topic>Memory - drug effects</topic><topic>Metabolism</topic><topic>Metabolites</topic><topic>Nutrition</topic><topic>Postprandial metabolism</topic><topic>Postprandial Period - physiology</topic><topic>Proteins</topic><topic>Reaction Time - drug effects</topic><topic>Respiratory Mechanics - physiology</topic><topic>Surveys and Questionnaires</topic><topic>Vertebrates: anatomy and physiology, studies on body, several organs or systems</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Fischer, Karina</creatorcontrib><creatorcontrib>Colombani, Paolo C.</creatorcontrib><creatorcontrib>Langhans, Wolfgang</creatorcontrib><creatorcontrib>Wenk, Caspar</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Immunology Abstracts</collection><collection>Agricultural Science Collection</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>Agricultural & Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Agricultural Science Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>Neurosciences Abstracts</collection><jtitle>British journal of nutrition</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Fischer, Karina</au><au>Colombani, Paolo C.</au><au>Langhans, Wolfgang</au><au>Wenk, Caspar</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cognitive performance and its relationship with postprandial metabolic changes after ingestion of different macronutrients in the morning</atitle><jtitle>British journal of nutrition</jtitle><addtitle>Br J Nutr</addtitle><date>2001-03-01</date><risdate>2001</risdate><volume>85</volume><issue>3</issue><spage>393</spage><epage>405</epage><pages>393-405</pages><issn>0007-1145</issn><eissn>1475-2662</eissn><coden>BJNUAV</coden><abstract>The effect of carbohydrate, protein and fat ingestion on simple as well as complex cognitive functions and the relationship between the respective postprandial metabolic changes and changes in cognitive performance were studied in fifteen healthy male students. Subjects were tested in three sessions, separated by 1 week, for short-term changes in blood variables, indirect calorimetry, subjective performance and different objective performance tasks using a repeated-measures counterbalanced cross-over design. Measurements were made after an overnight fast before and hourly during 3 h after test meal ingestion. Test meals consisted of either pure carbohydrates, protein or fat and were served as isoenergetic (1670 kJ) spoonable creams with similar sensory properties. Most aspects of subjective performance did not differ between test meals. For all objective tasks, however, postprandial cognitive performance was best after fat ingestion concomitant with an almost constant glucose metabolism and constant metabolic activation state measured by glucagon:insulin (G:I). In contrast, carbohydrate as well as protein ingestion resulted in lower overall cognitive performance, both together with partly marked changes (P<0.001) in glucose metabolism and metabolic activation. They also differently affected specific cognitive functions (P<0.05) in relation to their specific effect on metabolism. Carbohydrate ingestion resulted in relatively better short-term memory and accuracy of tasks concomitant with low metabolic activation, whereas protein ingestion resulted in better attention and efficiency of tasks concomitant with higher metabolic activation. Our findings support the concept that good and stable cognitive performance is related to a balanced glucose metabolism and metabolic activation state.</abstract><cop>Cambridge, UK</cop><pub>Cambridge University Press</pub><pmid>11299085</pmid><doi>10.1079/BJN2000269</doi><tpages>13</tpages><oa>free_for_read</oa></addata></record> |
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| ispartof | British journal of nutrition, 2001-03, Vol.85 (3), p.393-405 |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Free Full-Text Journals in Chemistry |
| subjects | Adult Biological and medical sciences Blood Glucose - metabolism Calorimetry Calorimetry, Indirect Carbohydrates Cognition & reasoning Cognition - drug effects Cognitive ability Cognitive performance Cross-Over Studies Diet - psychology Dietary Carbohydrates - pharmacology Dietary Fats - pharmacology Dietary Proteins - pharmacology Energy Metabolism - physiology Feeding. Feeding behavior Fundamental and applied biological sciences. Psychology Glucagon Glucagon - blood Glucose Hormones - blood Humans Ingestion Insulin - blood Macronutrient ingestion Male Meals Memory - drug effects Metabolism Metabolites Nutrition Postprandial metabolism Postprandial Period - physiology Proteins Reaction Time - drug effects Respiratory Mechanics - physiology Surveys and Questionnaires Vertebrates: anatomy and physiology, studies on body, several organs or systems |
| title | Cognitive performance and its relationship with postprandial metabolic changes after ingestion of different macronutrients in the morning |
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