Longitudinal Trends in Real-World Outcomes after Initiation of Ivacaftor. A Cohort Study from the Cystic Fibrosis Registry of Ireland

Patient registries have the potential to collect and analyze high-quality postauthorization data on new medicines. We used cystic fibrosis (CF) registry data to assess outcomes after the initiation of ivacaftor, a CF transmembrane conductance regulator (CFTR) potentiator approved for the treatment o...

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Veröffentlicht in:	Annals of the American Thoracic Society 2019-02, Vol.16 (2), p.209-216
Hauptverfasser:	Kirwan, Laura, Fletcher, Godfrey, Harrington, Mary, Jeleniewska, Paulina, Zhou, Shijun, Casserly, Brian, Gallagher, Charles G, Greally, Peter, Gunaratnam, Cedric, Herzig, Mary, Linnane, Barry, McElvaney, Noel Gerard, McKone, Edward F, McNally, Paul, Mullane, David, Ní Chróinín, Muireann, O'Mahony, Michael, Plant, Barry J, Jackson, Abaigeal D
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aminophenols - therapeutic use Anti-Bacterial Agents - administration & dosage Body Mass Index Child Cohort analysis Cystic fibrosis Cystic Fibrosis - drug therapy Cystic Fibrosis - genetics Cystic Fibrosis Transmembrane Conductance Regulator - genetics Female Forced Expiratory Volume Genetic Markers Hospitalization - statistics & numerical data Humans Ireland Longitudinal Studies Lung - drug effects Lung - physiopathology Male Middle Aged Mutation Quinolones - therapeutic use Registries Respiratory System Agents - therapeutic use Studies Treatment Outcome Young Adult
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