Developing definitions for invasive fungal diseases in critically ill adult patients in intensive care units. Protocol of the FUNgal infections Definitions in ICU patients (FUNDICU) project
Summary Background The reliability of diagnostic criteria for invasive fungal diseases (IFD) developed for severely immunocompromised patients is questionable in critically ill adult patients in intensive care units (ICU). Objectives To develop a standard set of definitions for IFD in critically ill...
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| Veröffentlicht in: | Mycoses 2019-04, Vol.62 (4), p.310-319 |
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| creator | Bassetti, Matteo Scudeller, Luigia Giacobbe, Daniele R. Lamoth, Frederic Righi, Elda Zuccaro, Valentina Grecchi, Cecilia Rebuffi, Chiara Akova, Murat Alastruey‐Izquierdo, Ana Arikan‐Akdagli, Sevtap Azoulay, Elie Blot, Stijn I. Cornely, Oliver A. Lass‐Flörl, Cornelia Koehler, Philipp Cuenca‐Estrella, Manuel de Lange, Dylan W. De Rosa, Francesco G. De Waele, Jan J. Dimopoulos, George Garnacho‐Montero, José Hoenigl, Martin Kanj, Souha S. Maertens, Johan Martin‐Loeches, Ignacio Muñoz, Patricia Kullberg, Bart J. Agvald‐Ohman, Christina Poulakou, Garyphallia Rello, Jordi Sanguinetti, Maurizio Taccone, Fabio S. Timsit, Jean‐François Torres, Antoni Vazquez, Jose A. Calandra, Thierry |
| description | Summary
Background
The reliability of diagnostic criteria for invasive fungal diseases (IFD) developed for severely immunocompromised patients is questionable in critically ill adult patients in intensive care units (ICU).
Objectives
To develop a standard set of definitions for IFD in critically ill adult patients in ICU.
Methods
Based on a systematic literature review, a list of potential definitions to be applied to ICU patients will be developed by the ESCMID Study Group for Infections in Critically Ill Patients (ESGCIP) and the ESCMID Fungal Infection Study Group (EFISG) chairpersons. The proposed definitions will be evaluated by a panel of 30 experts using the RAND/UCLA appropriateness methods. The panel will rank each of the proposed definitions on a 1‐9 scale trough a dedicated questionnaire, in two rounds: one remote and one face‐to‐face. Based on their median rank and the level of agreement across panel members, selected definitions will be organised in a main consensus document and in an executive summary. The executive summary will be made available online for public comments.
Conclusions
The present consensus project will seek to provide standard definitions for IFD in critically ill adult patients in ICU, with the ultimate aims of improving their clinical outcome and facilitating the comparison and generalizability of research findings. |
| doi_str_mv | 10.1111/myc.12869 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_2133439887</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2198507326</sourcerecordid><originalsourceid>FETCH-LOGICAL-p3149-95b0c3230d14f32295bdbec5799a9c6c1b3cc6ad576f93608648733f81c5a11d3</originalsourceid><addsrcrecordid>eNpdkctu2zAQRYmgReK4WeQHCgLdJAs5pChR4rKwkzZAmnRRL7oSaGqY0qBJVZQc-OPyb53Y6QPlho85986Al5BzzmYc19VmZ2Y8r6U6IhNeCJWxklVvyIQpIbKqYNUJOU1pzRivVC6PyYlgRS5LVU_I8wK24GPnwiNtwbrgBhdDojb21IWtTm4L1I7hUXvaugQ6QcICNT2CRnu_o857qtvRD7TTg4Mw7AEXBgh7tdE90BGN04x-7eMQTfQ0Wjr8AHqzvH9xdsGCOTRe_DME2tzOl39tLxBf4Msl7fq4RsU78tZqn-DsdZ-S5c31t_nn7O7h0-38413WCV6oTJUrZkQuWMsLK_Ic7-0KTFkppZWRhq-EMVK3ZSWtEpLVsqgrIWzNTak5b8WUXBx8se_PEdLQbFwy4L0OEMfU5FwI_PcaVVPy4T90Hcc-4HRIqRqDEblE6v0rNa420DZd7za63zW_g0Hg6gA8OQ-7P3XOmpfEG0y82SfefPk-3x_EL2ZBn6w</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2198507326</pqid></control><display><type>article</type><title>Developing definitions for invasive fungal diseases in critically ill adult patients in intensive care units. Protocol of the FUNgal infections Definitions in ICU patients (FUNDICU) project</title><source>Wiley Online Library Journals Frontfile Complete</source><creator>Bassetti, Matteo ; Scudeller, Luigia ; Giacobbe, Daniele R. ; Lamoth, Frederic ; Righi, Elda ; Zuccaro, Valentina ; Grecchi, Cecilia ; Rebuffi, Chiara ; Akova, Murat ; Alastruey‐Izquierdo, Ana ; Arikan‐Akdagli, Sevtap ; Azoulay, Elie ; Blot, Stijn I. ; Cornely, Oliver A. ; Lass‐Flörl, Cornelia ; Koehler, Philipp ; Cuenca‐Estrella, Manuel ; de Lange, Dylan W. ; De Rosa, Francesco G. ; De Waele, Jan J. ; Dimopoulos, George ; Garnacho‐Montero, José ; Hoenigl, Martin ; Kanj, Souha S. ; Maertens, Johan ; Martin‐Loeches, Ignacio ; Muñoz, Patricia ; Kullberg, Bart J. ; Agvald‐Ohman, Christina ; Poulakou, Garyphallia ; Rello, Jordi ; Sanguinetti, Maurizio ; Taccone, Fabio S. ; Timsit, Jean‐François ; Torres, Antoni ; Vazquez, Jose A. ; Calandra, Thierry</creator><creatorcontrib>Bassetti, Matteo ; Scudeller, Luigia ; Giacobbe, Daniele R. ; Lamoth, Frederic ; Righi, Elda ; Zuccaro, Valentina ; Grecchi, Cecilia ; Rebuffi, Chiara ; Akova, Murat ; Alastruey‐Izquierdo, Ana ; Arikan‐Akdagli, Sevtap ; Azoulay, Elie ; Blot, Stijn I. ; Cornely, Oliver A. ; Lass‐Flörl, Cornelia ; Koehler, Philipp ; Cuenca‐Estrella, Manuel ; de Lange, Dylan W. ; De Rosa, Francesco G. ; De Waele, Jan J. ; Dimopoulos, George ; Garnacho‐Montero, José ; Hoenigl, Martin ; Kanj, Souha S. ; Maertens, Johan ; Martin‐Loeches, Ignacio ; Muñoz, Patricia ; Kullberg, Bart J. ; Agvald‐Ohman, Christina ; Poulakou, Garyphallia ; Rello, Jordi ; Sanguinetti, Maurizio ; Taccone, Fabio S. ; Timsit, Jean‐François ; Torres, Antoni ; Vazquez, Jose A. ; Calandra, Thierry ; European Society of Intensive Care Medicine (ESICM) ; from the Study Group for Infections in Critically Ill Patients (ESGCIP) and the Fungal Infection Study Group (EFISG) of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) ; Mycoses Study Group Education and Research Consortium (MSGERC) ; European Confederation of Medical Mycology (ECMM)</creatorcontrib><description>Summary
Background
The reliability of diagnostic criteria for invasive fungal diseases (IFD) developed for severely immunocompromised patients is questionable in critically ill adult patients in intensive care units (ICU).
Objectives
To develop a standard set of definitions for IFD in critically ill adult patients in ICU.
Methods
Based on a systematic literature review, a list of potential definitions to be applied to ICU patients will be developed by the ESCMID Study Group for Infections in Critically Ill Patients (ESGCIP) and the ESCMID Fungal Infection Study Group (EFISG) chairpersons. The proposed definitions will be evaluated by a panel of 30 experts using the RAND/UCLA appropriateness methods. The panel will rank each of the proposed definitions on a 1‐9 scale trough a dedicated questionnaire, in two rounds: one remote and one face‐to‐face. Based on their median rank and the level of agreement across panel members, selected definitions will be organised in a main consensus document and in an executive summary. The executive summary will be made available online for public comments.
Conclusions
The present consensus project will seek to provide standard definitions for IFD in critically ill adult patients in ICU, with the ultimate aims of improving their clinical outcome and facilitating the comparison and generalizability of research findings.</description><identifier>ISSN: 0933-7407</identifier><identifier>EISSN: 1439-0507</identifier><identifier>DOI: 10.1111/myc.12869</identifier><identifier>PMID: 30426598</identifier><language>eng</language><publisher>Germany: Wiley Subscription Services, Inc</publisher><subject>Aspergillus ; biomarker ; Candida ; candidiasis ; cryptococcosis ; diagnosis ; Fungal diseases ; Immunocompromised hosts ; Intensive care ; Intensive care units ; Literature reviews ; pneumocystosis</subject><ispartof>Mycoses, 2019-04, Vol.62 (4), p.310-319</ispartof><rights>2018 Blackwell Verlag GmbH</rights><rights>2018 Blackwell Verlag GmbH.</rights><rights>2019 Blackwell Verlag GmbH</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><orcidid>0000-0002-2004-3724 ; 0000-0001-7240-9567 ; 0000-0003-4257-5980 ; 0000-0001-9599-3137 ; 0000-0002-7386-7495 ; 0000-0001-6413-3396 ; 0000-0002-1023-5597 ; 0000-0003-2385-1759 ; 0000-0001-8651-4405</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fmyc.12869$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fmyc.12869$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30426598$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bassetti, Matteo</creatorcontrib><creatorcontrib>Scudeller, Luigia</creatorcontrib><creatorcontrib>Giacobbe, Daniele R.</creatorcontrib><creatorcontrib>Lamoth, Frederic</creatorcontrib><creatorcontrib>Righi, Elda</creatorcontrib><creatorcontrib>Zuccaro, Valentina</creatorcontrib><creatorcontrib>Grecchi, Cecilia</creatorcontrib><creatorcontrib>Rebuffi, Chiara</creatorcontrib><creatorcontrib>Akova, Murat</creatorcontrib><creatorcontrib>Alastruey‐Izquierdo, Ana</creatorcontrib><creatorcontrib>Arikan‐Akdagli, Sevtap</creatorcontrib><creatorcontrib>Azoulay, Elie</creatorcontrib><creatorcontrib>Blot, Stijn I.</creatorcontrib><creatorcontrib>Cornely, Oliver A.</creatorcontrib><creatorcontrib>Lass‐Flörl, Cornelia</creatorcontrib><creatorcontrib>Koehler, Philipp</creatorcontrib><creatorcontrib>Cuenca‐Estrella, Manuel</creatorcontrib><creatorcontrib>de Lange, Dylan W.</creatorcontrib><creatorcontrib>De Rosa, Francesco G.</creatorcontrib><creatorcontrib>De Waele, Jan J.</creatorcontrib><creatorcontrib>Dimopoulos, George</creatorcontrib><creatorcontrib>Garnacho‐Montero, José</creatorcontrib><creatorcontrib>Hoenigl, Martin</creatorcontrib><creatorcontrib>Kanj, Souha S.</creatorcontrib><creatorcontrib>Maertens, Johan</creatorcontrib><creatorcontrib>Martin‐Loeches, Ignacio</creatorcontrib><creatorcontrib>Muñoz, Patricia</creatorcontrib><creatorcontrib>Kullberg, Bart J.</creatorcontrib><creatorcontrib>Agvald‐Ohman, Christina</creatorcontrib><creatorcontrib>Poulakou, Garyphallia</creatorcontrib><creatorcontrib>Rello, Jordi</creatorcontrib><creatorcontrib>Sanguinetti, Maurizio</creatorcontrib><creatorcontrib>Taccone, Fabio S.</creatorcontrib><creatorcontrib>Timsit, Jean‐François</creatorcontrib><creatorcontrib>Torres, Antoni</creatorcontrib><creatorcontrib>Vazquez, Jose A.</creatorcontrib><creatorcontrib>Calandra, Thierry</creatorcontrib><creatorcontrib>European Society of Intensive Care Medicine (ESICM)</creatorcontrib><creatorcontrib>from the Study Group for Infections in Critically Ill Patients (ESGCIP) and the Fungal Infection Study Group (EFISG) of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID)</creatorcontrib><creatorcontrib>Mycoses Study Group Education and Research Consortium (MSGERC)</creatorcontrib><creatorcontrib>European Confederation of Medical Mycology (ECMM)</creatorcontrib><title>Developing definitions for invasive fungal diseases in critically ill adult patients in intensive care units. Protocol of the FUNgal infections Definitions in ICU patients (FUNDICU) project</title><title>Mycoses</title><addtitle>Mycoses</addtitle><description>Summary
Background
The reliability of diagnostic criteria for invasive fungal diseases (IFD) developed for severely immunocompromised patients is questionable in critically ill adult patients in intensive care units (ICU).
Objectives
To develop a standard set of definitions for IFD in critically ill adult patients in ICU.
Methods
Based on a systematic literature review, a list of potential definitions to be applied to ICU patients will be developed by the ESCMID Study Group for Infections in Critically Ill Patients (ESGCIP) and the ESCMID Fungal Infection Study Group (EFISG) chairpersons. The proposed definitions will be evaluated by a panel of 30 experts using the RAND/UCLA appropriateness methods. The panel will rank each of the proposed definitions on a 1‐9 scale trough a dedicated questionnaire, in two rounds: one remote and one face‐to‐face. Based on their median rank and the level of agreement across panel members, selected definitions will be organised in a main consensus document and in an executive summary. The executive summary will be made available online for public comments.
Conclusions
The present consensus project will seek to provide standard definitions for IFD in critically ill adult patients in ICU, with the ultimate aims of improving their clinical outcome and facilitating the comparison and generalizability of research findings.</description><subject>Aspergillus</subject><subject>biomarker</subject><subject>Candida</subject><subject>candidiasis</subject><subject>cryptococcosis</subject><subject>diagnosis</subject><subject>Fungal diseases</subject><subject>Immunocompromised hosts</subject><subject>Intensive care</subject><subject>Intensive care units</subject><subject>Literature reviews</subject><subject>pneumocystosis</subject><issn>0933-7407</issn><issn>1439-0507</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><recordid>eNpdkctu2zAQRYmgReK4WeQHCgLdJAs5pChR4rKwkzZAmnRRL7oSaGqY0qBJVZQc-OPyb53Y6QPlho85986Al5BzzmYc19VmZ2Y8r6U6IhNeCJWxklVvyIQpIbKqYNUJOU1pzRivVC6PyYlgRS5LVU_I8wK24GPnwiNtwbrgBhdDojb21IWtTm4L1I7hUXvaugQ6QcICNT2CRnu_o857qtvRD7TTg4Mw7AEXBgh7tdE90BGN04x-7eMQTfQ0Wjr8AHqzvH9xdsGCOTRe_DME2tzOl39tLxBf4Msl7fq4RsU78tZqn-DsdZ-S5c31t_nn7O7h0-38413WCV6oTJUrZkQuWMsLK_Ic7-0KTFkppZWRhq-EMVK3ZSWtEpLVsqgrIWzNTak5b8WUXBx8se_PEdLQbFwy4L0OEMfU5FwI_PcaVVPy4T90Hcc-4HRIqRqDEblE6v0rNa420DZd7za63zW_g0Hg6gA8OQ-7P3XOmpfEG0y82SfefPk-3x_EL2ZBn6w</recordid><startdate>201904</startdate><enddate>201904</enddate><creator>Bassetti, Matteo</creator><creator>Scudeller, Luigia</creator><creator>Giacobbe, Daniele R.</creator><creator>Lamoth, Frederic</creator><creator>Righi, Elda</creator><creator>Zuccaro, Valentina</creator><creator>Grecchi, Cecilia</creator><creator>Rebuffi, Chiara</creator><creator>Akova, Murat</creator><creator>Alastruey‐Izquierdo, Ana</creator><creator>Arikan‐Akdagli, Sevtap</creator><creator>Azoulay, Elie</creator><creator>Blot, Stijn I.</creator><creator>Cornely, Oliver A.</creator><creator>Lass‐Flörl, Cornelia</creator><creator>Koehler, Philipp</creator><creator>Cuenca‐Estrella, Manuel</creator><creator>de Lange, Dylan W.</creator><creator>De Rosa, Francesco G.</creator><creator>De Waele, Jan J.</creator><creator>Dimopoulos, George</creator><creator>Garnacho‐Montero, José</creator><creator>Hoenigl, Martin</creator><creator>Kanj, Souha S.</creator><creator>Maertens, Johan</creator><creator>Martin‐Loeches, Ignacio</creator><creator>Muñoz, Patricia</creator><creator>Kullberg, Bart J.</creator><creator>Agvald‐Ohman, Christina</creator><creator>Poulakou, Garyphallia</creator><creator>Rello, Jordi</creator><creator>Sanguinetti, Maurizio</creator><creator>Taccone, Fabio S.</creator><creator>Timsit, Jean‐François</creator><creator>Torres, Antoni</creator><creator>Vazquez, Jose A.</creator><creator>Calandra, Thierry</creator><general>Wiley Subscription Services, Inc</general><scope>NPM</scope><scope>M7N</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-2004-3724</orcidid><orcidid>https://orcid.org/0000-0001-7240-9567</orcidid><orcidid>https://orcid.org/0000-0003-4257-5980</orcidid><orcidid>https://orcid.org/0000-0001-9599-3137</orcidid><orcidid>https://orcid.org/0000-0002-7386-7495</orcidid><orcidid>https://orcid.org/0000-0001-6413-3396</orcidid><orcidid>https://orcid.org/0000-0002-1023-5597</orcidid><orcidid>https://orcid.org/0000-0003-2385-1759</orcidid><orcidid>https://orcid.org/0000-0001-8651-4405</orcidid></search><sort><creationdate>201904</creationdate><title>Developing definitions for invasive fungal diseases in critically ill adult patients in intensive care units. Protocol of the FUNgal infections Definitions in ICU patients (FUNDICU) project</title><author>Bassetti, Matteo ; Scudeller, Luigia ; Giacobbe, Daniele R. ; Lamoth, Frederic ; Righi, Elda ; Zuccaro, Valentina ; Grecchi, Cecilia ; Rebuffi, Chiara ; Akova, Murat ; Alastruey‐Izquierdo, Ana ; Arikan‐Akdagli, Sevtap ; Azoulay, Elie ; Blot, Stijn I. ; Cornely, Oliver A. ; Lass‐Flörl, Cornelia ; Koehler, Philipp ; Cuenca‐Estrella, Manuel ; de Lange, Dylan W. ; De Rosa, Francesco G. ; De Waele, Jan J. ; Dimopoulos, George ; Garnacho‐Montero, José ; Hoenigl, Martin ; Kanj, Souha S. ; Maertens, Johan ; Martin‐Loeches, Ignacio ; Muñoz, Patricia ; Kullberg, Bart J. ; Agvald‐Ohman, Christina ; Poulakou, Garyphallia ; Rello, Jordi ; Sanguinetti, Maurizio ; Taccone, Fabio S. ; Timsit, Jean‐François ; Torres, Antoni ; Vazquez, Jose A. ; Calandra, Thierry</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p3149-95b0c3230d14f32295bdbec5799a9c6c1b3cc6ad576f93608648733f81c5a11d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Aspergillus</topic><topic>biomarker</topic><topic>Candida</topic><topic>candidiasis</topic><topic>cryptococcosis</topic><topic>diagnosis</topic><topic>Fungal diseases</topic><topic>Immunocompromised hosts</topic><topic>Intensive care</topic><topic>Intensive care units</topic><topic>Literature reviews</topic><topic>pneumocystosis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bassetti, Matteo</creatorcontrib><creatorcontrib>Scudeller, Luigia</creatorcontrib><creatorcontrib>Giacobbe, Daniele R.</creatorcontrib><creatorcontrib>Lamoth, Frederic</creatorcontrib><creatorcontrib>Righi, Elda</creatorcontrib><creatorcontrib>Zuccaro, Valentina</creatorcontrib><creatorcontrib>Grecchi, Cecilia</creatorcontrib><creatorcontrib>Rebuffi, Chiara</creatorcontrib><creatorcontrib>Akova, Murat</creatorcontrib><creatorcontrib>Alastruey‐Izquierdo, Ana</creatorcontrib><creatorcontrib>Arikan‐Akdagli, Sevtap</creatorcontrib><creatorcontrib>Azoulay, Elie</creatorcontrib><creatorcontrib>Blot, Stijn I.</creatorcontrib><creatorcontrib>Cornely, Oliver A.</creatorcontrib><creatorcontrib>Lass‐Flörl, Cornelia</creatorcontrib><creatorcontrib>Koehler, Philipp</creatorcontrib><creatorcontrib>Cuenca‐Estrella, Manuel</creatorcontrib><creatorcontrib>de Lange, Dylan W.</creatorcontrib><creatorcontrib>De Rosa, Francesco G.</creatorcontrib><creatorcontrib>De Waele, Jan J.</creatorcontrib><creatorcontrib>Dimopoulos, George</creatorcontrib><creatorcontrib>Garnacho‐Montero, José</creatorcontrib><creatorcontrib>Hoenigl, Martin</creatorcontrib><creatorcontrib>Kanj, Souha S.</creatorcontrib><creatorcontrib>Maertens, Johan</creatorcontrib><creatorcontrib>Martin‐Loeches, Ignacio</creatorcontrib><creatorcontrib>Muñoz, Patricia</creatorcontrib><creatorcontrib>Kullberg, Bart J.</creatorcontrib><creatorcontrib>Agvald‐Ohman, Christina</creatorcontrib><creatorcontrib>Poulakou, Garyphallia</creatorcontrib><creatorcontrib>Rello, Jordi</creatorcontrib><creatorcontrib>Sanguinetti, Maurizio</creatorcontrib><creatorcontrib>Taccone, Fabio S.</creatorcontrib><creatorcontrib>Timsit, Jean‐François</creatorcontrib><creatorcontrib>Torres, Antoni</creatorcontrib><creatorcontrib>Vazquez, Jose A.</creatorcontrib><creatorcontrib>Calandra, Thierry</creatorcontrib><creatorcontrib>European Society of Intensive Care Medicine (ESICM)</creatorcontrib><creatorcontrib>from the Study Group for Infections in Critically Ill Patients (ESGCIP) and the Fungal Infection Study Group (EFISG) of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID)</creatorcontrib><creatorcontrib>Mycoses Study Group Education and Research Consortium (MSGERC)</creatorcontrib><creatorcontrib>European Confederation of Medical Mycology (ECMM)</creatorcontrib><collection>PubMed</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>MEDLINE - Academic</collection><jtitle>Mycoses</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bassetti, Matteo</au><au>Scudeller, Luigia</au><au>Giacobbe, Daniele R.</au><au>Lamoth, Frederic</au><au>Righi, Elda</au><au>Zuccaro, Valentina</au><au>Grecchi, Cecilia</au><au>Rebuffi, Chiara</au><au>Akova, Murat</au><au>Alastruey‐Izquierdo, Ana</au><au>Arikan‐Akdagli, Sevtap</au><au>Azoulay, Elie</au><au>Blot, Stijn I.</au><au>Cornely, Oliver A.</au><au>Lass‐Flörl, Cornelia</au><au>Koehler, Philipp</au><au>Cuenca‐Estrella, Manuel</au><au>de Lange, Dylan W.</au><au>De Rosa, Francesco G.</au><au>De Waele, Jan J.</au><au>Dimopoulos, George</au><au>Garnacho‐Montero, José</au><au>Hoenigl, Martin</au><au>Kanj, Souha S.</au><au>Maertens, Johan</au><au>Martin‐Loeches, Ignacio</au><au>Muñoz, Patricia</au><au>Kullberg, Bart J.</au><au>Agvald‐Ohman, Christina</au><au>Poulakou, Garyphallia</au><au>Rello, Jordi</au><au>Sanguinetti, Maurizio</au><au>Taccone, Fabio S.</au><au>Timsit, Jean‐François</au><au>Torres, Antoni</au><au>Vazquez, Jose A.</au><au>Calandra, Thierry</au><aucorp>European Society of Intensive Care Medicine (ESICM)</aucorp><aucorp>from the Study Group for Infections in Critically Ill Patients (ESGCIP) and the Fungal Infection Study Group (EFISG) of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID)</aucorp><aucorp>Mycoses Study Group Education and Research Consortium (MSGERC)</aucorp><aucorp>European Confederation of Medical Mycology (ECMM)</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Developing definitions for invasive fungal diseases in critically ill adult patients in intensive care units. Protocol of the FUNgal infections Definitions in ICU patients (FUNDICU) project</atitle><jtitle>Mycoses</jtitle><addtitle>Mycoses</addtitle><date>2019-04</date><risdate>2019</risdate><volume>62</volume><issue>4</issue><spage>310</spage><epage>319</epage><pages>310-319</pages><issn>0933-7407</issn><eissn>1439-0507</eissn><abstract>Summary
Background
The reliability of diagnostic criteria for invasive fungal diseases (IFD) developed for severely immunocompromised patients is questionable in critically ill adult patients in intensive care units (ICU).
Objectives
To develop a standard set of definitions for IFD in critically ill adult patients in ICU.
Methods
Based on a systematic literature review, a list of potential definitions to be applied to ICU patients will be developed by the ESCMID Study Group for Infections in Critically Ill Patients (ESGCIP) and the ESCMID Fungal Infection Study Group (EFISG) chairpersons. The proposed definitions will be evaluated by a panel of 30 experts using the RAND/UCLA appropriateness methods. The panel will rank each of the proposed definitions on a 1‐9 scale trough a dedicated questionnaire, in two rounds: one remote and one face‐to‐face. Based on their median rank and the level of agreement across panel members, selected definitions will be organised in a main consensus document and in an executive summary. The executive summary will be made available online for public comments.
Conclusions
The present consensus project will seek to provide standard definitions for IFD in critically ill adult patients in ICU, with the ultimate aims of improving their clinical outcome and facilitating the comparison and generalizability of research findings.</abstract><cop>Germany</cop><pub>Wiley Subscription Services, Inc</pub><pmid>30426598</pmid><doi>10.1111/myc.12869</doi><tpages>10</tpages><orcidid>https://orcid.org/0000-0002-2004-3724</orcidid><orcidid>https://orcid.org/0000-0001-7240-9567</orcidid><orcidid>https://orcid.org/0000-0003-4257-5980</orcidid><orcidid>https://orcid.org/0000-0001-9599-3137</orcidid><orcidid>https://orcid.org/0000-0002-7386-7495</orcidid><orcidid>https://orcid.org/0000-0001-6413-3396</orcidid><orcidid>https://orcid.org/0000-0002-1023-5597</orcidid><orcidid>https://orcid.org/0000-0003-2385-1759</orcidid><orcidid>https://orcid.org/0000-0001-8651-4405</orcidid><oa>free_for_read</oa></addata></record> |
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| ispartof | Mycoses, 2019-04, Vol.62 (4), p.310-319 |
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| language | eng |
| recordid | cdi_proquest_miscellaneous_2133439887 |
| source | Wiley Online Library Journals Frontfile Complete |
| subjects | Aspergillus biomarker Candida candidiasis cryptococcosis diagnosis Fungal diseases Immunocompromised hosts Intensive care Intensive care units Literature reviews pneumocystosis |
| title | Developing definitions for invasive fungal diseases in critically ill adult patients in intensive care units. Protocol of the FUNgal infections Definitions in ICU patients (FUNDICU) project |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-13T03%3A09%3A43IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Developing%20definitions%20for%20invasive%20fungal%20diseases%20in%20critically%20ill%20adult%20patients%20in%20intensive%20care%20units.%20Protocol%20of%20the%20FUNgal%20infections%20Definitions%20in%20ICU%20patients%20(FUNDICU)%20project&rft.jtitle=Mycoses&rft.au=Bassetti,%20Matteo&rft.aucorp=European%20Society%20of%20Intensive%20Care%20Medicine%20(ESICM)&rft.date=2019-04&rft.volume=62&rft.issue=4&rft.spage=310&rft.epage=319&rft.pages=310-319&rft.issn=0933-7407&rft.eissn=1439-0507&rft_id=info:doi/10.1111/myc.12869&rft_dat=%3Cproquest_pubme%3E2198507326%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2198507326&rft_id=info:pmid/30426598&rfr_iscdi=true |