Molecular Mechanisms of Phosphodiesterase-5 Inhibitors on Neuronal Apoptosis

Phosphodiesterase-5 inhibitors (PDE5Is) have been shown to modulate cell death/cell survival in different in vivo and in vitro models of disease by activating many signaling pathways. This review aimed at elucidating how PDE5Is can inhibit apoptosis. In this study, we describe many signaling pathway...

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Veröffentlicht in:	DNA and cell biology 2018-11, Vol.37 (11), p.861-865
Hauptverfasser:	Duarte-Silva, Eduardo, Peixoto, Christina Alves
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Cell death Cell survival Inhibitors Molecular modelling Phosphodiesterase Signal transduction Signaling Survival
Online-Zugang:	Volltext
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