4E-BP1 is a target of Smad4 essential for TGFb-mediated inhibition of cell proliferation

Assembly of the multi-subunit eukaryotic translation initiation factor-4F (eIF4F) is critical for protein synthesis and cell growth and proliferation. eIF4F formation is regulated by the translation-inhibitory protein 4E-BP1. While proliferation factors and intracellular pathways that impinge upon 4...

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Veröffentlicht in:	The EMBO journal 2009-11, Vol.28 (22), p.3514-3522
Hauptverfasser:	Azar, Rania, Alard, Amandine, Susini, Christiane, Bousquet, Corinne, Pyronnet, Stephane
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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