Entrapment of herbal extracts into biodegradable microcapsules
The microcapsules with entrapped herbal water-soluble extracts of plantain Plantago major and calendula Calendula officinalis L. (PCE) were prepared by layer-by-layer (LbL)-adsorption of carrageenan and oligochitosan onto CaCO 3 microparticles with their subsequent dissolving after the treatment of...
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| Veröffentlicht in: | Biochemistry (Moscow). Supplement. Series B, Biomedical chemistry Biomedical chemistry, 2008-06, Vol.2 (2), p.176-182 |
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| container_title | Biochemistry (Moscow). Supplement. Series B, Biomedical chemistry |
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| creator | Borodina, T. N. Rumsh, L. D. Kunizhev, S. M. Sukhorukov, G. B. Vorozhtsov, G. N. Feldman, B. M. Rusanova, A. V. Vasil’eva, T. V. Strukova, S. M. Markvicheva, E. A. |
| description | The microcapsules with entrapped herbal water-soluble extracts of plantain
Plantago major
and calendula
Calendula officinalis
L. (PCE) were prepared by layer-by-layer (LbL)-adsorption of carrageenan and oligochitosan onto CaCO
3
microparticles with their subsequent dissolving after the treatment of EDTA. Entrapment of PCE was performed by using adsorption and co-precipitation techniques. The co-precipitation provided better entrapment of PCE into the carbonate matrix compared to adsorption. In vitro release kinetics (AGJ) was studied using artificial gastric juice. Using the model of acetate ulcer in rats it has been demonstrated that PCE released from the microcapsules accelerates gastric tissue repair. |
| doi_str_mv | 10.1134/S199075080802008X |
| format | Article |
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Plantago major
and calendula
Calendula officinalis
L. (PCE) were prepared by layer-by-layer (LbL)-adsorption of carrageenan and oligochitosan onto CaCO
3
microparticles with their subsequent dissolving after the treatment of EDTA. Entrapment of PCE was performed by using adsorption and co-precipitation techniques. The co-precipitation provided better entrapment of PCE into the carbonate matrix compared to adsorption. In vitro release kinetics (AGJ) was studied using artificial gastric juice. Using the model of acetate ulcer in rats it has been demonstrated that PCE released from the microcapsules accelerates gastric tissue repair.</description><identifier>ISSN: 1990-7508</identifier><identifier>EISSN: 1990-7516</identifier><identifier>DOI: 10.1134/S199075080802008X</identifier><language>eng</language><publisher>Dordrecht: SP MAIK Nauka/Interperiodica</publisher><subject>Biodegradation ; Bioorganic Chemistry ; Calendula officinalis ; Chemistry ; Chemistry and Materials Science ; Experimental Studies ; Herbs ; Kinetics ; Medicinal Chemistry ; Pharmacology ; Plantago major</subject><ispartof>Biochemistry (Moscow). Supplement. Series B, Biomedical chemistry, 2008-06, Vol.2 (2), p.176-182</ispartof><rights>MAIK Nauka 2008</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c346t-b9b1d3ce34f3d1c8a3b71905710cf99051a2207aa026bf13fced2bc7cb41d1b3</citedby><cites>FETCH-LOGICAL-c346t-b9b1d3ce34f3d1c8a3b71905710cf99051a2207aa026bf13fced2bc7cb41d1b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1134/S199075080802008X$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1134/S199075080802008X$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids></links><search><creatorcontrib>Borodina, T. N.</creatorcontrib><creatorcontrib>Rumsh, L. D.</creatorcontrib><creatorcontrib>Kunizhev, S. M.</creatorcontrib><creatorcontrib>Sukhorukov, G. B.</creatorcontrib><creatorcontrib>Vorozhtsov, G. N.</creatorcontrib><creatorcontrib>Feldman, B. M.</creatorcontrib><creatorcontrib>Rusanova, A. V.</creatorcontrib><creatorcontrib>Vasil’eva, T. V.</creatorcontrib><creatorcontrib>Strukova, S. M.</creatorcontrib><creatorcontrib>Markvicheva, E. A.</creatorcontrib><title>Entrapment of herbal extracts into biodegradable microcapsules</title><title>Biochemistry (Moscow). Supplement. Series B, Biomedical chemistry</title><addtitle>Biochem. Moscow Suppl. Ser. B</addtitle><description>The microcapsules with entrapped herbal water-soluble extracts of plantain
Plantago major
and calendula
Calendula officinalis
L. (PCE) were prepared by layer-by-layer (LbL)-adsorption of carrageenan and oligochitosan onto CaCO
3
microparticles with their subsequent dissolving after the treatment of EDTA. Entrapment of PCE was performed by using adsorption and co-precipitation techniques. The co-precipitation provided better entrapment of PCE into the carbonate matrix compared to adsorption. In vitro release kinetics (AGJ) was studied using artificial gastric juice. Using the model of acetate ulcer in rats it has been demonstrated that PCE released from the microcapsules accelerates gastric tissue repair.</description><subject>Biodegradation</subject><subject>Bioorganic Chemistry</subject><subject>Calendula officinalis</subject><subject>Chemistry</subject><subject>Chemistry and Materials Science</subject><subject>Experimental Studies</subject><subject>Herbs</subject><subject>Kinetics</subject><subject>Medicinal Chemistry</subject><subject>Pharmacology</subject><subject>Plantago major</subject><issn>1990-7508</issn><issn>1990-7516</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp1kE1LxDAQhoMouK7-AG_Fg7dqJkm_LoIs6wcseHAP3kKSTtYubVOTFvTfm2VFRJE5zDA878s7Q8g50CsALq6foapokdEyFqO0fDkgs90qLTLID79nWh6TkxC2lObAKzEjN8t-9GrosB8TZ5NX9Fq1Cb7HpRlD0vSjS3Tjatx4VSvdYtI1xjujhjC1GE7JkVVtwLOvPifru-V68ZCunu4fF7er1HCRj6muNNTcIBeW12BKxXUBFc0KoMbGZBkoxmihFGW5tsCtwZppUxgtoAbN5-Rybzt49zZhGGXXBINtq3p0U5AMOMsELyN48Qvcusn3MZqEKsu5EIxFCPZQPCQEj1YOvumU_5BA5e6b8s83o4btNSGy_Qb9D-N_RZ-o7nbG</recordid><startdate>20080601</startdate><enddate>20080601</enddate><creator>Borodina, T. 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Plantago major
and calendula
Calendula officinalis
L. (PCE) were prepared by layer-by-layer (LbL)-adsorption of carrageenan and oligochitosan onto CaCO
3
microparticles with their subsequent dissolving after the treatment of EDTA. Entrapment of PCE was performed by using adsorption and co-precipitation techniques. The co-precipitation provided better entrapment of PCE into the carbonate matrix compared to adsorption. In vitro release kinetics (AGJ) was studied using artificial gastric juice. Using the model of acetate ulcer in rats it has been demonstrated that PCE released from the microcapsules accelerates gastric tissue repair.</abstract><cop>Dordrecht</cop><pub>SP MAIK Nauka/Interperiodica</pub><doi>10.1134/S199075080802008X</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1990-7508 |
| ispartof | Biochemistry (Moscow). Supplement. Series B, Biomedical chemistry, 2008-06, Vol.2 (2), p.176-182 |
| issn | 1990-7508 1990-7516 |
| language | eng |
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| source | SpringerLink |
| subjects | Biodegradation Bioorganic Chemistry Calendula officinalis Chemistry Chemistry and Materials Science Experimental Studies Herbs Kinetics Medicinal Chemistry Pharmacology Plantago major |
| title | Entrapment of herbal extracts into biodegradable microcapsules |
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