Angiotensinogen M235T Gene Polymorphism is a Genetic Determinant of Cerebrovascular and Cardiopulmonary Morbidity in Adolescents with Sickle Cell Disease

Cerebrovascular stroke is a common critical complication of sickle cell disease (SCD). Angiotensinogen (AGT) M235T gene polymorphism is associated with risk of ischemic stroke and cardiovascular disease. We investigated the potential association between angiotensinogen M235T gene polymorphism and su...

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Veröffentlicht in:	Journal of stroke and cerebrovascular diseases 2019-02, Vol.28 (2), p.441-449
Hauptverfasser:	ElAlfy, Mohsen Saleh, Ebeid, Fatma Soliman Elsayed, Kamal, Tarek Mostafa, Eissa, Deena Samir, Ismail, Eman Abdel Rahman, Mohamed, Samar Hassan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Age Factors Anemia, Sickle Cell - diagnosis Anemia, Sickle Cell - epidemiology Anemia, Sickle Cell - genetics Angiotensinogen - genetics angiotensinogen M235T gene polymorphism cardiopulomonary complications Case-Control Studies Cerebrovascular Disorders - diagnosis Cerebrovascular Disorders - epidemiology Cerebrovascular Disorders - genetics Egypt - epidemiology Female Gene Frequency Genes, Modifier Genetic Association Studies Genetic Predisposition to Disease Heart Diseases - diagnosis Heart Diseases - epidemiology Heart Diseases - genetics Humans Lung Diseases - diagnosis Lung Diseases - epidemiology Lung Diseases - genetics Male Phenotype Polymorphism, Genetic Risk Factors Sickle cell disease stroke Young Adult
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