Co-delivery of siRNA and etoposide to cancer cells using an MDEA esterquat based drug delivery system

Cancer has become the leading cause of death in many countries. Chemotherapy is a key component in the treatment of most cancers but has limited efficacy if the cancer develops resistance to the treatment over time and recur. RNA interference may be used to reduce the production of the proteins resp...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	European journal of pharmaceutical sciences 2019-01, Vol.127, p.142-150
Hauptverfasser:	Popova, Petya, Notabi, Martine Khataei, Code, Christian, Arnspang, Eva C., Andersen, Morten Østergaard
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents, Phytogenic - administration & dosage Cancer Cell Line, Tumor Combined Modality Therapy DOPE Drug Delivery Systems Etoposide Etoposide - administration & dosage Gene Silencing Green Fluorescent Proteins - genetics Humans MDEA Nanoparticles Neoplasms - therapy Quaternary Ammonium Compounds - administration & dosage RNA interference RNA, Small Interfering - administration & dosage siRNA
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!