Innate immune crosstalk in asthmatic airways: Innate lymphoid cells coordinate polarization of lung macrophages

Recent studies have emphasized the role of innate lymphoid cells (ILCs) in the development of asthma. The involvement of group 2 innate lymphoid cells (ILC2s) in asthma is well studied: however, the participation of other types of ILCs in the development of asthma remains unclear. This study aims to...

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Veröffentlicht in:	Journal of allergy and clinical immunology 2019-05, Vol.143 (5), p.1769-1782.e11
Hauptverfasser:	Kim, Jihyun, Chang, Yuna, Bae, Boram, Sohn, Kyoung-Hee, Cho, Sang-Heon, Chung, Doo Hyun, Kang, Hye Ryun, Kim, Hye Young
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Alveoli Animals Asthma Asthma - immunology asthma phenotype Cell adhesion Cell Differentiation Cells, Cultured Coculture Techniques Cytokines Cytokines - metabolism Eosinophilia - immunology Female Flow Cytometry Humans Immunity, Innate induced sputum Inflammation innate lymphoid cells Leukocytes (eosinophilic) Lung - immunology Lungs Lymphocytes - immunology Lymphoid cells macrophage Macrophages Macrophages, Alveolar - immunology Male Medical research Mice Mice, Inbred C57BL Middle Aged Neutrophils Phenotypes Polarization Sputum Sputum - immunology Steroids Th2 Cells - immunology
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