CircRNA circPDSS1 promotes the gastric cancer progression by sponging miR‐186‐5p and modulating NEK2

The aim of this study is to investigate the regulatory mechanism of circPDSS1/miR‐186‐5p/NEK2 axis on the viability and proliferation in gastric cancer (GC) cell line. Differentially expressed circRNAs, miRNAs, and mRNAs in GC tissues and paracarcinoma tissues were analyzed using gene chips GSE83521...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of cellular physiology 2019-07, Vol.234 (7), p.10458-10469
Hauptverfasser:	Ouyang, Yiming, Li, Yuejin, Huang, Yingguang, Li, Xing, Zhu, Yu, Long, Yaxin, Wang, Yongzhi, Guo, Xiaodong, Gong, Kunmei
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Apoptosis - genetics Bioinformatics Biomarkers Biomarkers, Tumor - genetics Cancer Cell cycle Cell Cycle - genetics Cell Line, Tumor Cell Proliferation - genetics circPDSS1 Disease Progression Flow cytometry Gastric cancer gastric cancer (GC) Gene expression Gene Expression Regulation, Neoplastic - genetics Humans Medical prognosis MicroRNAs - genetics miR‐186‐5p NEK2 NIMA-Related Kinases - genetics Polymerase chain reaction Prognosis Regulatory mechanisms (biology) RNA, Circular - genetics Signal Transduction - genetics Stomach Neoplasms - genetics Stomach Neoplasms - pathology Survival analysis Therapeutic applications Viability
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!