Interleukin‐18 and diabetic nephropathy: A review

The inflammatory response has an important role in the pathophysiology of diabetic nephropathy that is contributed to by inflammatory mediators such as interleukin‐1 (IL‐1), IL‐6, IL‐18, tumor necrosis factor‐α, and macrophage chemotactic protein‐1; however, the role of IL‐18 seems to be more specif...

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Veröffentlicht in:	Journal of cellular physiology 2019-05, Vol.234 (5), p.5674-5682
Hauptverfasser:	Yaribeygi, Habib, Atkin, Stephen L., Sahebkar, Amirhossein
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents - therapeutic use Apoptosis Blood Glucose - metabolism Cytokines Diabetes Diabetes mellitus Diabetic Nephropathies - drug therapy Diabetic Nephropathies - immunology Diabetic Nephropathies - metabolism Diabetic nephropathy Disease Progression Excretion Glucose Humans Hyperglycemia Inflammation Inflammation Mediators - antagonists & inhibitors Inflammation Mediators - immunology Inflammation Mediators - metabolism Inflammatory response Interleukin-18 - antagonists & inhibitors Interleukin-18 - immunology Interleukin-18 - metabolism Interleukins interleukin‐18 Kidney - drug effects Kidney - immunology Kidney - metabolism Macrophages Nephropathy Oxidative stress Proteins Signal Transduction tumor necrosis factor‐α
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