Palliative treatment of germ cell cancer
•For the first time a definition of palliative is provided for germ-cell cancer patients. To our knowledge, this has never been attempted before.•We give a comprehensive review on treatment options.•We provide a clear algorithm for choosing palliative treatments.•We give expert advise on how to appr...
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Veröffentlicht in: | Cancer treatment reviews 2018-12, Vol.71, p.102-107 |
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container_title | Cancer treatment reviews |
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creator | Oing, Christoph Giannatempo, Patrizia Honecker, Friedemann Oechsle, Karin Bokemeyer, Carsten Beyer, Jörg |
description | •For the first time a definition of palliative is provided for germ-cell cancer patients. To our knowledge, this has never been attempted before.•We give a comprehensive review on treatment options.•We provide a clear algorithm for choosing palliative treatments.•We give expert advise on how to approach a patient before being declared palliative.
Most patients with metastatic germ-cell cancer (GCC) can be cured by cisplatin-based combination chemotherapy. Yet, about 10–15% of metastatic GCC patients will eventually die of their disease. This narrative review focuses on treatment options when cure is no longer realistic. |
doi_str_mv | 10.1016/j.ctrv.2018.10.007 |
format | Article |
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Most patients with metastatic germ-cell cancer (GCC) can be cured by cisplatin-based combination chemotherapy. Yet, about 10–15% of metastatic GCC patients will eventually die of their disease. This narrative review focuses on treatment options when cure is no longer realistic.</description><subject>Antineoplastic Agents - therapeutic use</subject><subject>Antineoplastic Combined Chemotherapy Protocols - therapeutic use</subject><subject>Bone Neoplasms - secondary</subject><subject>Bone Neoplasms - therapy</subject><subject>Brain Neoplasms - secondary</subject><subject>Brain Neoplasms - therapy</subject><subject>Drug therapy</subject><subject>Germ cell cancer</subject><subject>Germ cell tumor</subject><subject>Humans</subject><subject>Immunotherapy - methods</subject><subject>Molecular Targeted Therapy - methods</subject><subject>Neoplasms, Germ Cell and Embryonal - pathology</subject><subject>Neoplasms, Germ Cell and Embryonal - therapy</subject><subject>Palliative Care - methods</subject><subject>Palliative treatment</subject><subject>Peripheral Nervous System Diseases - etiology</subject><subject>Platinum-refractory</subject><subject>Psychosocial Support Systems</subject><issn>0305-7372</issn><issn>1532-1967</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kEtLAzEUhYMotlb_gAuZZTdT85hkEnAjxRcUdKHrkGTuSMpMpyZpwX9vhlaXbu6FwzmHez-ErgleEEzE7XrhUtgvKCYyCwuM6xM0JZzRkihRn6IpZpiXNavpBF3EuMYYKybUOZowXBFOsJii-ZvpOm-S30ORApjUwyYVQ1t8QugLB11XOLNxEC7RWWu6CFfHPUMfjw_vy-dy9fr0srxfla6iIpUAihjDHakdU0IxblvKgXNqpROWt4wSIxWRhnCRZ6OspK0ltlK2lrZybIbmh95tGL52EJPufRzvMBsYdlFTwiitpKQqW-nB6sIQY4BWb4PvTfjWBOuRkF7rkZAeCY1aJpRDN8f-ne2h-Yv8IsmGu4MB8pd7D0FH5yEjaHwAl3Qz-P_6fwBg93XH</recordid><startdate>20181201</startdate><enddate>20181201</enddate><creator>Oing, Christoph</creator><creator>Giannatempo, Patrizia</creator><creator>Honecker, Friedemann</creator><creator>Oechsle, Karin</creator><creator>Bokemeyer, Carsten</creator><creator>Beyer, Jörg</creator><general>Elsevier Ltd</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-5578-3418</orcidid><orcidid>https://orcid.org/0000-0003-1755-9700</orcidid></search><sort><creationdate>20181201</creationdate><title>Palliative treatment of germ cell cancer</title><author>Oing, Christoph ; 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subjects | Antineoplastic Agents - therapeutic use Antineoplastic Combined Chemotherapy Protocols - therapeutic use Bone Neoplasms - secondary Bone Neoplasms - therapy Brain Neoplasms - secondary Brain Neoplasms - therapy Drug therapy Germ cell cancer Germ cell tumor Humans Immunotherapy - methods Molecular Targeted Therapy - methods Neoplasms, Germ Cell and Embryonal - pathology Neoplasms, Germ Cell and Embryonal - therapy Palliative Care - methods Palliative treatment Peripheral Nervous System Diseases - etiology Platinum-refractory Psychosocial Support Systems |
title | Palliative treatment of germ cell cancer |
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