Palliative treatment of germ cell cancer

•For the first time a definition of palliative is provided for germ-cell cancer patients. To our knowledge, this has never been attempted before.•We give a comprehensive review on treatment options.•We provide a clear algorithm for choosing palliative treatments.•We give expert advise on how to appr...

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Veröffentlicht in:Cancer treatment reviews 2018-12, Vol.71, p.102-107
Hauptverfasser: Oing, Christoph, Giannatempo, Patrizia, Honecker, Friedemann, Oechsle, Karin, Bokemeyer, Carsten, Beyer, Jörg
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container_end_page 107
container_issue
container_start_page 102
container_title Cancer treatment reviews
container_volume 71
creator Oing, Christoph
Giannatempo, Patrizia
Honecker, Friedemann
Oechsle, Karin
Bokemeyer, Carsten
Beyer, Jörg
description •For the first time a definition of palliative is provided for germ-cell cancer patients. To our knowledge, this has never been attempted before.•We give a comprehensive review on treatment options.•We provide a clear algorithm for choosing palliative treatments.•We give expert advise on how to approach a patient before being declared palliative. Most patients with metastatic germ-cell cancer (GCC) can be cured by cisplatin-based combination chemotherapy. Yet, about 10–15% of metastatic GCC patients will eventually die of their disease. This narrative review focuses on treatment options when cure is no longer realistic.
doi_str_mv 10.1016/j.ctrv.2018.10.007
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subjects Antineoplastic Agents - therapeutic use
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Bone Neoplasms - secondary
Bone Neoplasms - therapy
Brain Neoplasms - secondary
Brain Neoplasms - therapy
Drug therapy
Germ cell cancer
Germ cell tumor
Humans
Immunotherapy - methods
Molecular Targeted Therapy - methods
Neoplasms, Germ Cell and Embryonal - pathology
Neoplasms, Germ Cell and Embryonal - therapy
Palliative Care - methods
Palliative treatment
Peripheral Nervous System Diseases - etiology
Platinum-refractory
Psychosocial Support Systems
title Palliative treatment of germ cell cancer
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