TLR Activation Alters Bone Marrow-Derived Macrophage Differentiation

Early exposure to inflammatory signals may have a lasting impact on immune function. Present throughout embryogenesis, macrophages are key cells providing innate immune protection to the developing fetus and newborn. Here, we have used an established model of macrophage development to test how early...

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Veröffentlicht in:	Journal of innate immunity 2019-01, Vol.11 (1), p.99-108
Hauptverfasser:	Oppong-Nonterah, Gertrude O., Lakhdari, Omar, Yamamura, Asami, Hoffman, Hal M., Prince, Lawrence S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, Differentiation - immunology Antigens, Differentiation - metabolism Calcium-Binding Proteins - metabolism Cell Differentiation - drug effects Escherichia coli I-kappa B Kinase - metabolism Immunity, Innate Lipopolysaccharides - pharmacology Macrophage Activation - drug effects Macrophages - cytology Macrophages - immunology Macrophages - metabolism Mice Mitogen-Activated Protein Kinases - metabolism Phagocytosis - drug effects Receptors, G-Protein-Coupled - metabolism Receptors, Granulocyte-Macrophage Colony-Stimulating Factor - metabolism Research Article Signal Transduction Toll-Like Receptors - metabolism
Online-Zugang:	Volltext
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