Knockdown of peroxisome proliferator-activated receptor-b induces less differentiation and enhances cell-fibronectin adhesion of colon cancer cells

The role of peroxisome proliferator-activated receptor-b/d (PPAR-b/d) in the pathogenesis of colon cancer remains highly controversial. This study specifically silenced the PPAR-b expression in three colon cancer cell lines with different metastatic potentials. Although PPAR-b knockdown resulted in...

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Veröffentlicht in:Oncogene 2010-01, Vol.29 (4), p.516-526
Hauptverfasser: Yang, L, Olsson, B, Pfeifer, D, Joensson, J -I, Zhou, Z -G, Jiang, X, Fredriksson, B -A, Zhang, H, Sun, X -F
Format: Artikel
Sprache:eng
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