Hepatitis C Virus-Linked Mitochondrial Dysfunction Promotes Hypoxia-Inducible Factor 1-Mediated Glycolytic Adaptation

Hepatitis C virus (HCV) infection induces a state of oxidative stress by affecting mitochondrial-respiratory-chain activity. By using cell lines inducibly expressing different HCV constructs, we showed previously that viral-protein expression leads to severe impairment of mitochondrial oxidative pho...

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Veröffentlicht in:	Journal of virology 2010-01, Vol.84 (1), p.647-660
Hauptverfasser:	Ripoli, Maria, D'Aprile, Annamaria, Quarato, Giovanni, Sarasin-Filipowicz, Magdalena, Gouttenoire, Jerome, Scrima, Rosella, Cela, Olga, Boffoli, Domenico, Heim, Markus H, Moradpour, Darius, Capitanio, Nazzareno, Piccoli, Claudia
Format:	Artikel
Sprache:	eng
Schlagworte:	Hepatitis C virus
Online-Zugang:	Volltext
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