Chemical and Biomolecule Sensing with Organic Field-Effect Transistors

The strong and controllable chemical sensitivity of organic semiconductors (OSCs) and the amplification capability of transistors in circuits make use of OSC-based field-effect transistors compelling for chemical sensors. Analytes detected and assayed range from few-atom gas-phase molecules that may...

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Veröffentlicht in:Chemical reviews 2019-01, Vol.119 (1), p.3-35
Hauptverfasser: Li, Hui, Shi, Wei, Song, Jian, Jang, Hyun-June, Dailey, Jennifer, Yu, Junsheng, Katz, Howard E
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container_issue 1
container_start_page 3
container_title Chemical reviews
container_volume 119
creator Li, Hui
Shi, Wei
Song, Jian
Jang, Hyun-June
Dailey, Jennifer
Yu, Junsheng
Katz, Howard E
description The strong and controllable chemical sensitivity of organic semiconductors (OSCs) and the amplification capability of transistors in circuits make use of OSC-based field-effect transistors compelling for chemical sensors. Analytes detected and assayed range from few-atom gas-phase molecules that may have adverse health and security implications to biomacromolecules (proteins, nucleic acids) that may be markers for physiological processes and medical conditions. This review highlights recent progress in organic field-effect transistor (OFET) chemical sensors, emphasizing advances from the past 5 years and including aspects of OSC morphology and the role of adjacent dielectrics. Design elements of the OSCs and various formats for the devices are illustrated and evaluated. Challenges associated with the present state of the art and future opportunities are also discussed.
doi_str_mv 10.1021/acs.chemrev.8b00016
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source ACS Publications; MEDLINE
subjects Biosensing Techniques
Biosensors
Chemical sensors
Dielectrics
Electronics industry
Field effect transistors
Morphology
Nucleic acids
Nucleic Acids - analysis
Organic Chemicals - chemistry
Organic chemistry
Organic semiconductors
Physiology
Proteins
Proteins - analysis
Security
Semiconductor devices
Semiconductors
Sensors
Transistors
Transistors, Electronic
title Chemical and Biomolecule Sensing with Organic Field-Effect Transistors
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