Vitamin D Supplementation in Pregnancy and Lactation and Infant Growth
To the Editor: Roth et al. (August 9 issue) 1 report that prenatal and postpartum vitamin D supplementation has no significant effect on the anthropometric measurements of offspring, birth outcomes, or morbidity at 1 year of age. A crucial limitation of the trial, highlighted by the authors, is that...
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| Veröffentlicht in: | The New England journal of medicine 2018-11, Vol.379 (19), p.1880-1881 |
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| container_end_page | 1881 |
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| container_issue | 19 |
| container_start_page | 1880 |
| container_title | The New England journal of medicine |
| container_volume | 379 |
| creator | Hewison, Martin Wagner, Carol L Hollis, Bruce W Roth, Daniel E Gernand, Alison D Al Mahmud, Abdullah |
| description | To the Editor:
Roth et al. (August 9 issue)
1
report that prenatal and postpartum vitamin D supplementation has no significant effect on the anthropometric measurements of offspring, birth outcomes, or morbidity at 1 year of age. A crucial limitation of the trial, highlighted by the authors, is that supplementation was initiated at 17 to 24 weeks of gestation, even though vitamin D concentrations appear to be most influential much earlier in pregnancy. Increased rates of pregnancy and live birth have been reported for women with elevated serum concentrations of 25-hydroxyvitamin D before conception but not at week 8 of gestation.
2
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| doi_str_mv | 10.1056/NEJMc1812157 |
| format | Article |
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Roth et al. (August 9 issue)
1
report that prenatal and postpartum vitamin D supplementation has no significant effect on the anthropometric measurements of offspring, birth outcomes, or morbidity at 1 year of age. A crucial limitation of the trial, highlighted by the authors, is that supplementation was initiated at 17 to 24 weeks of gestation, even though vitamin D concentrations appear to be most influential much earlier in pregnancy. Increased rates of pregnancy and live birth have been reported for women with elevated serum concentrations of 25-hydroxyvitamin D before conception but not at week 8 of gestation.
2
. . .</description><identifier>ISSN: 0028-4793</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJMc1812157</identifier><identifier>PMID: 30403950</identifier><language>eng</language><publisher>United States: Massachusetts Medical Society</publisher><subject>Gestation ; Lactation ; Morbidity ; Postpartum ; Pregnancy ; Supplements ; Vitamin D ; Vitamin deficiency</subject><ispartof>The New England journal of medicine, 2018-11, Vol.379 (19), p.1880-1881</ispartof><rights>Copyright © 2018 Massachusetts Medical Society. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c296t-f1b2b463621250e34e87cb78b6625161786b0422e3f7920ac9d983f558128ca13</citedby><cites>FETCH-LOGICAL-c296t-f1b2b463621250e34e87cb78b6625161786b0422e3f7920ac9d983f558128ca13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.nejm.org/doi/pdf/10.1056/NEJMc1812157$$EPDF$$P50$$Gmms$$H</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/2130854445?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,780,784,2759,2760,26103,27924,27925,52382,54064,64385,64387,64389,72469</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30403950$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hewison, Martin</creatorcontrib><creatorcontrib>Wagner, Carol L</creatorcontrib><creatorcontrib>Hollis, Bruce W</creatorcontrib><creatorcontrib>Roth, Daniel E</creatorcontrib><creatorcontrib>Gernand, Alison D</creatorcontrib><creatorcontrib>Al Mahmud, Abdullah</creatorcontrib><title>Vitamin D Supplementation in Pregnancy and Lactation and Infant Growth</title><title>The New England journal of medicine</title><addtitle>N Engl J Med</addtitle><description>To the Editor:
Roth et al. (August 9 issue)
1
report that prenatal and postpartum vitamin D supplementation has no significant effect on the anthropometric measurements of offspring, birth outcomes, or morbidity at 1 year of age. A crucial limitation of the trial, highlighted by the authors, is that supplementation was initiated at 17 to 24 weeks of gestation, even though vitamin D concentrations appear to be most influential much earlier in pregnancy. Increased rates of pregnancy and live birth have been reported for women with elevated serum concentrations of 25-hydroxyvitamin D before conception but not at week 8 of gestation.
2
. . .</description><subject>Gestation</subject><subject>Lactation</subject><subject>Morbidity</subject><subject>Postpartum</subject><subject>Pregnancy</subject><subject>Supplements</subject><subject>Vitamin D</subject><subject>Vitamin deficiency</subject><issn>0028-4793</issn><issn>1533-4406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqNkUtLw0AQgBdRbK3ePEtADx6M7ju7R6ltrdQH-LiGzXajKd1N3E2Q_nsTWkXEg3MZZubjg5kB4BDBcwQZv7gb3dxqJBBGLNkCfcQIiSmFfBv0IcQipokkPbAXwgK2gajcBT0CKSSSwT4YvxS1soWLrqLHpqqWxhpXq7ooXdQ2H7x5dcrpVaTcPJopvRl11dTlytXRxJcf9ds-2MnVMpiDTR6A5_HoaXgdz-4n0-HlLNZY8jrOUYYzygnHCDNoCDUi0VkiMs4xQxwlgmeQYmxInkgMlZZzKUjOWLue0AqRAThdeytfvjcm1KktgjbLpXKmbEKKEUGYEsjZP1EscWc9_oUuysa7dpGOgoJRSjvh2ZrSvgzBmzytfGGVX6UIpt0r0p-vaPGjjbTJrJl_w1-3b4GTNWBtSJ1Z2L89n0Uniqo</recordid><startdate>20181108</startdate><enddate>20181108</enddate><creator>Hewison, Martin</creator><creator>Wagner, Carol L</creator><creator>Hollis, Bruce W</creator><creator>Roth, Daniel E</creator><creator>Gernand, Alison D</creator><creator>Al Mahmud, Abdullah</creator><general>Massachusetts Medical Society</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0TZ</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K0Y</scope><scope>LK8</scope><scope>M0R</scope><scope>M0T</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>M2P</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20181108</creationdate><title>Vitamin D Supplementation in Pregnancy and Lactation and Infant Growth</title><author>Hewison, Martin ; Wagner, Carol L ; Hollis, Bruce W ; Roth, Daniel E ; Gernand, Alison D ; Al Mahmud, Abdullah</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c296t-f1b2b463621250e34e87cb78b6625161786b0422e3f7920ac9d983f558128ca13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Gestation</topic><topic>Lactation</topic><topic>Morbidity</topic><topic>Postpartum</topic><topic>Pregnancy</topic><topic>Supplements</topic><topic>Vitamin D</topic><topic>Vitamin deficiency</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hewison, Martin</creatorcontrib><creatorcontrib>Wagner, Carol L</creatorcontrib><creatorcontrib>Hollis, Bruce W</creatorcontrib><creatorcontrib>Roth, Daniel E</creatorcontrib><creatorcontrib>Gernand, Alison D</creatorcontrib><creatorcontrib>Al Mahmud, Abdullah</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>Pharma and Biotech Premium PRO</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>eLibrary</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>New England Journal of Medicine</collection><collection>ProQuest Biological Science Collection</collection><collection>Consumer Health Database</collection><collection>Healthcare Administration Database</collection><collection>Medical Database</collection><collection>Psychology Database</collection><collection>Research Library</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>The New England journal of medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hewison, Martin</au><au>Wagner, Carol L</au><au>Hollis, Bruce W</au><au>Roth, Daniel E</au><au>Gernand, Alison D</au><au>Al Mahmud, Abdullah</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Vitamin D Supplementation in Pregnancy and Lactation and Infant Growth</atitle><jtitle>The New England journal of medicine</jtitle><addtitle>N Engl J Med</addtitle><date>2018-11-08</date><risdate>2018</risdate><volume>379</volume><issue>19</issue><spage>1880</spage><epage>1881</epage><pages>1880-1881</pages><issn>0028-4793</issn><eissn>1533-4406</eissn><abstract>To the Editor:
Roth et al. (August 9 issue)
1
report that prenatal and postpartum vitamin D supplementation has no significant effect on the anthropometric measurements of offspring, birth outcomes, or morbidity at 1 year of age. A crucial limitation of the trial, highlighted by the authors, is that supplementation was initiated at 17 to 24 weeks of gestation, even though vitamin D concentrations appear to be most influential much earlier in pregnancy. Increased rates of pregnancy and live birth have been reported for women with elevated serum concentrations of 25-hydroxyvitamin D before conception but not at week 8 of gestation.
2
. . .</abstract><cop>United States</cop><pub>Massachusetts Medical Society</pub><pmid>30403950</pmid><doi>10.1056/NEJMc1812157</doi><tpages>2</tpages></addata></record> |
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| ispartof | The New England journal of medicine, 2018-11, Vol.379 (19), p.1880-1881 |
| issn | 0028-4793 1533-4406 |
| language | eng |
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| source | EZB-FREE-00999 freely available EZB journals; ProQuest Central UK/Ireland; New England Journal of Medicine |
| subjects | Gestation Lactation Morbidity Postpartum Pregnancy Supplements Vitamin D Vitamin deficiency |
| title | Vitamin D Supplementation in Pregnancy and Lactation and Infant Growth |
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