The endogenous opioid system modulates defensive behavior evoked by Crotalus durissus terrificus: Panicolytic-like effect of intracollicular non-selective opioid receptors blockade

Background: There is a controversy regarding the key role played by opioid peptide neurotransmission in the modulation of panic-attack-related responses. Aims: Using a prey versus rattlesnakes paradigm, the present work investigated the involvement of the endogenous opioid peptide-mediated system of...

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Veröffentlicht in:	Journal of psychopharmacology (Oxford) 2019-01, Vol.33 (1), p.51-61
Hauptverfasser:	Calvo, Fabrício, Lobão-Soares, Bruno, de Freitas, Renato Leonardo, Paschoalin-Maurin, Tatiana, dos Anjos-Garcia, Tayllon, Medeiros, Priscila, da Silva, Juliana Almeida, Lovick, Thelma Anderson, Coimbra, Norberto Cysne
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anxiety Avoidance Learning - drug effects Conditioning Crotalus Crotalus durissus terrificus Defense Mechanisms Defensive behavior Escape Reaction - drug effects Exposure Fear - drug effects Fear - psychology Fear conditioning Inferior Colliculi - drug effects Inferior Colliculi - physiology Inferior colliculus Male Naloxone Naloxone - pharmacology Narcotics Neuromodulation Neurotransmission Opioid Peptides - antagonists & inhibitors Opioid Peptides - physiology Opioid receptors Panic Panic attacks Panic Disorder - drug therapy Peptides Prey Rats Rats, Wistar Snakes
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