Injectable angiogenic and osteogenic carrageenan nanocomposite hydrogel for bone tissue engineering

Functional biomaterials that couple angiogenesis and osteogenesis processes are vital for bone tissue engineering and bone remodeling. Herein we developed an injectable carrageenan nanocomposite hydrogel incorporated with whitlockite nanoparticles and an angiogenic drug, dimethyloxallylglycine. Synt...

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Veröffentlicht in:	International journal of biological macromolecules 2019-02, Vol.122, p.320-328
Hauptverfasser:	Yegappan, Ramanathan, Selvaprithiviraj, Vignesh, Amirthalingam, Sivashanmugam, Mohandas, Annapoorna, Hwang, Nathaniel S., Jayakumar, R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Bone and Bones - cytology Bone and Bones - drug effects Bone and Bones - physiology Carrageenan - administration & dosage Carrageenan - chemistry Carrageenan - pharmacology Carrageenan hydrogel Cell Differentiation - drug effects Cell Proliferation - drug effects Dimethyloxallylglycine Human Umbilical Vein Endothelial Cells - cytology Human Umbilical Vein Endothelial Cells - drug effects Humans Hydrogels - chemistry Injections Nanocomposites Neovascularization, Physiologic - drug effects Osteogenesis Osteogenesis - drug effects Tissue Engineering Whitlockite nanoparticles
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