Berberine mitigates high glucose-potentiated platelet aggregation and apoptosis by modulating aldose reductase and NADPH oxidase activity

Diabetes mellitus (DM) is a serious metabolic disorder affecting millions of people worldwide. The high rate of mortality and morbidity during DM is attributed to the increased atherothrombotic events due to platelet activation and apoptosis leading to macro and micro vascular occlusions. The platel...

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Veröffentlicht in:Free radical biology & medicine 2019-01, Vol.130, p.196-205
Hauptverfasser: Paul, Manoj, Hemshekhar, Mahadevappa, Kemparaju, Kempaiah, Girish, Kesturu S.
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Sprache:eng
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