Is it Possible to Implant HeartMate 3 Less Invasively? New Pump, New Approach

HeartMate 3 (HM3) left ventricular assist device (LVAD) is a compact, intrapericardial, centrifugal flow pump with a fully magnetically levitated rotor and a wide range of operation (2–10 L/min) to accommodate a broad range of clinical needs. We analyzed our experience with Heartware VAD (HVAD) and...

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Veröffentlicht in:Artificial organs 2018-12, Vol.42 (12), p.1132-1138
Hauptverfasser: Kocabeyoglu, Sinan Sabit, Kervan, Umit, Sert, Dogan Emre, Unal, Ertekin Utku, Demirkan, Burcu, Guray, Yesim, Aygun, Emre, Beyazal, Osman Fehmi, Karahan, Mehmet, Pac, Mustafa
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container_end_page 1138
container_issue 12
container_start_page 1132
container_title Artificial organs
container_volume 42
creator Kocabeyoglu, Sinan Sabit
Kervan, Umit
Sert, Dogan Emre
Unal, Ertekin Utku
Demirkan, Burcu
Guray, Yesim
Aygun, Emre
Beyazal, Osman Fehmi
Karahan, Mehmet
Pac, Mustafa
description HeartMate 3 (HM3) left ventricular assist device (LVAD) is a compact, intrapericardial, centrifugal flow pump with a fully magnetically levitated rotor and a wide range of operation (2–10 L/min) to accommodate a broad range of clinical needs. We analyzed our experience with Heartware VAD (HVAD) and HM3 implantation through minimally invasive left thoracotomy (MILT) and upper minimal J sternotomy. Between March 2015 and October 2016, 31 patients who underwent LVAD implantation through MILT were included in this study. Twenty‐three patients had HVAD (Group A) implantation, whereas 8 patients had HM3 (Group B). To compare outcomes of these pumps, measures were; mortality, cardiopulmonary bypass (CPB) time, duration of mechanical ventilatory support, blood loss and transfusion, intensive care unit (ICU) stay, right ventricular failure (RVF) and requirement of support with temporary devices, stroke, pump thrombosis, gastrointestinal bleeding and driveline infection rates. Interagency Registry for Mechanically Assisted Circulatory Support profiles, Pennsylvania and Michigan Risk Scores, right ventricular stroke work index and central venous pressure/pulmonary capillary wedge pressure ratio did not differ between these two groups. There was no difference in the length of ICU stay (P = 0.056), post‐operative blood product administration (P = 0.701), total time on mechanical ventilation (P = 0.386), RVF (P = 1) or duration of CPB (P = 0.836). In‐hospital cerebrovascular event rate was 13% in Group A and 0% in Group B, respectively. The HM3 assist system can be successfully implanted with minimally invasive techniques. This technique has proved to be safe and reproducible, with good clinical outcomes. Further, large collaborative studies are needed to identify the advantages of this approach.
doi_str_mv 10.1111/aor.13289
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Between March 2015 and October 2016, 31 patients who underwent LVAD implantation through MILT were included in this study. Twenty‐three patients had HVAD (Group A) implantation, whereas 8 patients had HM3 (Group B). To compare outcomes of these pumps, measures were; mortality, cardiopulmonary bypass (CPB) time, duration of mechanical ventilatory support, blood loss and transfusion, intensive care unit (ICU) stay, right ventricular failure (RVF) and requirement of support with temporary devices, stroke, pump thrombosis, gastrointestinal bleeding and driveline infection rates. Interagency Registry for Mechanically Assisted Circulatory Support profiles, Pennsylvania and Michigan Risk Scores, right ventricular stroke work index and central venous pressure/pulmonary capillary wedge pressure ratio did not differ between these two groups. There was no difference in the length of ICU stay (P = 0.056), post‐operative blood product administration (P = 0.701), total time on mechanical ventilation (P = 0.386), RVF (P = 1) or duration of CPB (P = 0.836). In‐hospital cerebrovascular event rate was 13% in Group A and 0% in Group B, respectively. The HM3 assist system can be successfully implanted with minimally invasive techniques. This technique has proved to be safe and reproducible, with good clinical outcomes. 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To compare outcomes of these pumps, measures were; mortality, cardiopulmonary bypass (CPB) time, duration of mechanical ventilatory support, blood loss and transfusion, intensive care unit (ICU) stay, right ventricular failure (RVF) and requirement of support with temporary devices, stroke, pump thrombosis, gastrointestinal bleeding and driveline infection rates. Interagency Registry for Mechanically Assisted Circulatory Support profiles, Pennsylvania and Michigan Risk Scores, right ventricular stroke work index and central venous pressure/pulmonary capillary wedge pressure ratio did not differ between these two groups. There was no difference in the length of ICU stay (P = 0.056), post‐operative blood product administration (P = 0.701), total time on mechanical ventilation (P = 0.386), RVF (P = 1) or duration of CPB (P = 0.836). In‐hospital cerebrovascular event rate was 13% in Group A and 0% in Group B, respectively. 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subjects Bleeding
Blood transfusion
Capillary pressure
Centrifugal pumps
Health risks
Heart
Heart surgery
Implantation
Left ventricular assist device
Mechanical circulatory support
Mechanical ventilation
Minimally invasive
Ostomy
Patients
Pressure
Pressure ratio
Right ventricular failure
Thoracotomy
Thromboembolism
Thrombosis
Transfusion
Ventilation
Ventricle
title Is it Possible to Implant HeartMate 3 Less Invasively? New Pump, New Approach
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