DNA molecules deviate from shortest trajectory when driven through hydrogel

Dynamic fluorescence-based single-molecule imaging of λ-DNA molecules driven through agarose hydrogels by DC electric fields reveals that passage through the hydrogel (98.5% water content) induces mobility orthogonal to the external field. Tortuous paths followed by the DNA molecules, which are heav...

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Veröffentlicht in:	The Journal of chemical physics 2018-10, Vol.149 (16), p.163331-163331
Hauptverfasser:	Guan, Juan, Chen, Kejia, Jee, Ah-Young, Granick, Steve
Format:	Artikel
Sprache:	eng
Schlagworte:	Deoxyribonucleic acid DNA DNA - chemistry Electric fields Field strength Fluorescence Hydrogels Hydrogels - chemistry Microscopy, Fluorescence Moisture content Normalizing Trajectories
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