Pannexin-3 Deficiency Delays Skin Wound Healing in Mice due to Defects in Channel Functionality

Pannexin-3 (Panx3) is a gap junction protein that is required for regulating cell cycle exit and the differentiation of osteoblasts and chondrocytes during skeletal development. However, the role of Panx3 in skin tissue regeneration remains unclear. After dorsal skin punch biopsies, Panx3-knockout m...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of investigative dermatology 2019-04, Vol.139 (4), p.909-918
Hauptverfasser:	Zhang, Peipei, Ishikawa, Masaki, Rhodes, Craig, Doyle, Andrew, Ikeuchi, Tomoko, Nakamura, Kuniyuki, Chiba, Yuta, He, Bing, Yamada, Yoshihiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Differentiation Cell Line Cell Movement Cell Proliferation Collagen - metabolism Connexins - biosynthesis Connexins - deficiency Connexins - genetics Connexins - metabolism Disease Models, Animal Endoplasmic Reticulum - metabolism Gap Junctions - metabolism Gene Expression Regulation Keratinocytes - metabolism Keratinocytes - pathology Mice Mice, Knockout RNA - genetics Signal Transduction Skin - injuries Skin - metabolism Skin - pathology Wound Healing
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!