Secretory phospholipase A sub(2) promotes MMP-9-mediated cell death by degrading type I collagen via the ERK pathway at an early stage of chondrogenesis

Background information. sPLA sub(2) (secretory phospholipase A sub(2)) has been implicated in a wide range of cellular responses, including cell proliferation and ECM (extracellular matrix) remodelling. Even though ECM remodelling is an essential step for chondrogenesis, the expression and functions...

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Veröffentlicht in:Biology of the cell 2010-02, Vol.102 (2), p.107-118
Hauptverfasser: Choi, Y-A, Kim, D-K, Bang, O-S, Kang, S-S, Jin, E-J
Format: Artikel
Sprache:eng
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