Secretory phospholipase A sub(2) promotes MMP-9-mediated cell death by degrading type I collagen via the ERK pathway at an early stage of chondrogenesis
Background information. sPLA sub(2) (secretory phospholipase A sub(2)) has been implicated in a wide range of cellular responses, including cell proliferation and ECM (extracellular matrix) remodelling. Even though ECM remodelling is an essential step for chondrogenesis, the expression and functions...
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Veröffentlicht in: | Biology of the cell 2010-02, Vol.102 (2), p.107-118 |
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Hauptverfasser: | , , , , |
Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
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