Ras activation contributes to the maintenance and expansion of Sca-1 super(pos) cells in a mouse model of breast cancer

The cancer stem cell (CSC) hypothesis proposes that CSCs are the root of cancer and cause cancer metastasis and recurrence. In this study, we examined whether Ras signaling is associated with stemness of the CSCs population characterized by the stem cell antigen (Sca-1) phenotype in a 4T1 syngeneic...

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Veröffentlicht in:	Cancer letters 2010-01, Vol.287 (2), p.172-181
Hauptverfasser:	Kim, Ran-Ju, Kim, Soo-Rim, Roh, Kyung-Jin, Park, Sang-Bum, Park, Jeong-Ran, Kang, Kyung-Sun, Kong, Gu, Tang, Binwu, Yang, Yu-An, Kohn, Ethan A, Wakefield, Lalage M, Nam, Jeong-Seok
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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