MHC class II fine tuning by ubiquitination: lesson from MARCHs

Ubiquitination, a posttranscriptional modification, has been known to contribute to many aspects of cellular event (e.g., protein quality control, signal transduction). In 2007 and 2016, we reported physiological E3 ubiquitin ligases for MHC class II; these are membrane-associated ring-CH-type finge...

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Veröffentlicht in:	Immunogenetics (New York) 2019-03, Vol.71 (3), p.197-201
Hauptverfasser:	Ishido, Satoshi, Kajikawa, Mizuho
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergology Animals Biology and Evolution of Antigen Presentation Biomedical and Life Sciences Biomedicine Cell Biology Epithelial cells Gene Function Histocompatibility Antigens Class II - chemistry Histocompatibility Antigens Class II - immunology Histocompatibility Antigens Class II - metabolism Human Genetics Humans Immunology Major histocompatibility complex Organs Post-transcription Proteins Quality control Review RNA Processing, Post-Transcriptional Signal quality Signal Transduction Thymus Ubiquitin Ubiquitin - metabolism Ubiquitin-protein ligase Ubiquitin-Protein Ligases - metabolism Ubiquitination
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