An Optimized Bistable Metabolic Switch To Decouple Phenotypic States during Anaerobic Fermentation

Metabolic engineers aim to genetically modify microorganisms to improve their ability to produce valuable compounds. Despite the prevalence of growth-coupled production processes, these strategies can significantly limit production rates. Instead, rates can be improved by decoupling and optimizing g...

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Veröffentlicht in:ACS synthetic biology 2018-12, Vol.7 (12), p.2854-2866
Hauptverfasser: Venayak, Naveen, Raj, Kaushik, Jaydeep, Rohil, Mahadevan, Radhakrishnan
Format: Artikel
Sprache:eng
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