Stroke in HIV infection and AIDS

HIV/AIDS appears to increase the risk of both ischemic and hemorrhagic stroke. This increased risk is most apparent in the young HIV-infected population in which other risk factors for stroke are seldom evident. Mechanisms underlying the increased risk include opportunistic infectious meningitides a...

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Veröffentlicht in:Expert review of cardiovascular therapy 2009-10, Vol.7 (10), p.1263-1271
Hauptverfasser: Dobbs, Michael R, Berger, Joseph R
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description HIV/AIDS appears to increase the risk of both ischemic and hemorrhagic stroke. This increased risk is most apparent in the young HIV-infected population in which other risk factors for stroke are seldom evident. Mechanisms underlying the increased risk include opportunistic infectious meningitides and vasculitides, primary HIV vasculopathy, altered coagulation and cardioembolic events, although the cause may be multifactorial or remain cryptic. With better control of HIV via effective, highly active antiretroviral therapy, the role of many of these risks has been mitigated, only to be supplanted by an aging population with more conventional atherosclerotic risk factors magnified by the hyperlipidemia attending the use of protease inhibitors. Selecting the appropriate therapy for treating stroke in the HIV-infected patient is dependent on diagnostic rigor in identifying its underlying etiology.
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identifier ISSN: 1477-9072
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subjects AIDS
AIDS (Disease)
Control
Development and progression
epidemiology
Highly active antiretroviral therapy
HIV
HIV (Viruses)
HIV patients
Human immunodeficiency virus
intracerebral hemorrhage
Protease inhibitors
Proteases
Risk factors
stroke
vasculopathy
title Stroke in HIV infection and AIDS
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