Effect of Zinc Acetate Dihydrate (NobelzinR) Treatment on Anemia and Taste Disorders in Patients with Chronic Kidney Disease with Hypozincemia
Some patients with chronic kidney disease (CKD) receiving hemodialysis develop erythropoietin-resistant anemia, possibly due to zinc deficiency. The frequency of zinc deficiency in CKD (stages 1-5 and 5D) and CKD improvement via zinc supplementation are not completely verified. Here 500 CKD patients...
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| Veröffentlicht in: | Acta medica Okayama 2018-10, Vol.72 (5), p.535-538 |
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| container_title | Acta medica Okayama |
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| creator | Sato, Daisuke Gohda, Tomohito Kihara, Masao Kanaguchi, Yasuhiko Kobayashi, Takashi Mano, Satoshi Sasaki, Yu Nohara, Nao Murakoshi, Maki Nakata, Junichiro Suzuki, Hitoshi Ueda, Seiji Horikoshi, Satoshi Suzuki, Yusuke |
| description | Some patients with chronic kidney disease (CKD) receiving hemodialysis develop erythropoietin-resistant anemia, possibly due to zinc deficiency. The frequency of zinc deficiency in CKD (stages 1-5 and 5D) and CKD improvement via zinc supplementation are not completely verified. Here 500 CKD patients (Stage 1/2, n=100; Stage 3, n=100; Stage 4, n=100, Stage n=5, 100; Stage 5D, n=100) will be recruited to determine the frequency of serum zinc deficiency at each CKD stage. Patients with serum zinc concentrations |
| doi_str_mv | 10.18926/AMO/56254 |
| format | Article |
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The frequency of zinc deficiency in CKD (stages 1-5 and 5D) and CKD improvement via zinc supplementation are not completely verified. Here 500 CKD patients (Stage 1/2, n=100; Stage 3, n=100; Stage 4, n=100, Stage n=5, 100; Stage 5D, n=100) will be recruited to determine the frequency of serum zinc deficiency at each CKD stage. Patients with serum zinc concentrations <80 μg/dL will be treated with zinc acetate dihydrate (NobelzinR) to evaluate its effects on hypozincemia, taste disturbances, and anemia.</description><identifier>ISSN: 0386-300X</identifier><identifier>DOI: 10.18926/AMO/56254</identifier><identifier>PMID: 30369613</identifier><language>eng</language><publisher>Japan</publisher><subject>Adult ; Aged ; Anemia - drug therapy ; Cross-Sectional Studies ; Humans ; Middle Aged ; Renal Insufficiency, Chronic - blood ; Renal Insufficiency, Chronic - complications ; Taste Disorders - drug therapy ; Young Adult ; Zinc - blood ; Zinc - deficiency ; Zinc Acetate - therapeutic use</subject><ispartof>Acta medica Okayama, 2018-10, Vol.72 (5), p.535-538</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,27905,27906</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30369613$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sato, Daisuke</creatorcontrib><creatorcontrib>Gohda, Tomohito</creatorcontrib><creatorcontrib>Kihara, Masao</creatorcontrib><creatorcontrib>Kanaguchi, Yasuhiko</creatorcontrib><creatorcontrib>Kobayashi, Takashi</creatorcontrib><creatorcontrib>Mano, Satoshi</creatorcontrib><creatorcontrib>Sasaki, Yu</creatorcontrib><creatorcontrib>Nohara, Nao</creatorcontrib><creatorcontrib>Murakoshi, Maki</creatorcontrib><creatorcontrib>Nakata, Junichiro</creatorcontrib><creatorcontrib>Suzuki, Hitoshi</creatorcontrib><creatorcontrib>Ueda, Seiji</creatorcontrib><creatorcontrib>Horikoshi, Satoshi</creatorcontrib><creatorcontrib>Suzuki, Yusuke</creatorcontrib><title>Effect of Zinc Acetate Dihydrate (NobelzinR) Treatment on Anemia and Taste Disorders in Patients with Chronic Kidney Disease with Hypozincemia</title><title>Acta medica Okayama</title><addtitle>Acta Med Okayama</addtitle><description>Some patients with chronic kidney disease (CKD) receiving hemodialysis develop erythropoietin-resistant anemia, possibly due to zinc deficiency. The frequency of zinc deficiency in CKD (stages 1-5 and 5D) and CKD improvement via zinc supplementation are not completely verified. Here 500 CKD patients (Stage 1/2, n=100; Stage 3, n=100; Stage 4, n=100, Stage n=5, 100; Stage 5D, n=100) will be recruited to determine the frequency of serum zinc deficiency at each CKD stage. Patients with serum zinc concentrations <80 μg/dL will be treated with zinc acetate dihydrate (NobelzinR) to evaluate its effects on hypozincemia, taste disturbances, and anemia.</description><subject>Adult</subject><subject>Aged</subject><subject>Anemia - drug therapy</subject><subject>Cross-Sectional Studies</subject><subject>Humans</subject><subject>Middle Aged</subject><subject>Renal Insufficiency, Chronic - blood</subject><subject>Renal Insufficiency, Chronic - complications</subject><subject>Taste Disorders - drug therapy</subject><subject>Young Adult</subject><subject>Zinc - blood</subject><subject>Zinc - deficiency</subject><subject>Zinc Acetate - therapeutic use</subject><issn>0386-300X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1kE1OwzAQRr0A0VLYcADkZVmE-idxkmVUCkUUilCREJvIcSaqq8QptisUDsGZSaGsZjTfm6fRIHRByTVNUiYm2eNyEgkWhUdoSHgiAk7I2wCdOrchhIWpICdowAkXqaB8iL5nVQXK47bC79oonCnw0gO-0euutPtu_NQWUH9p83KFVxakb8D0vMGZgUZLLE2JV9L97rjWlmAd1gY_S6970OFP7dd4urat0Qo_6NJAtydBOvjL5t227fVqbztDx5WsHZwf6gi93s5W03mwWN7dT7NFsOFh5ANeSs7iolAyjmR_f8QToP0kYqEiBa1ARFWcylByApQxEjMVEcEKzlLCIJF8hMZ_3q1tP3bgfN5op6CupYF253JGmUgpF0nSo5cHdFc0UOZbqxtpu_z_h_wHvgtxYQ</recordid><startdate>20181001</startdate><enddate>20181001</enddate><creator>Sato, Daisuke</creator><creator>Gohda, Tomohito</creator><creator>Kihara, Masao</creator><creator>Kanaguchi, Yasuhiko</creator><creator>Kobayashi, Takashi</creator><creator>Mano, Satoshi</creator><creator>Sasaki, Yu</creator><creator>Nohara, Nao</creator><creator>Murakoshi, Maki</creator><creator>Nakata, Junichiro</creator><creator>Suzuki, Hitoshi</creator><creator>Ueda, Seiji</creator><creator>Horikoshi, Satoshi</creator><creator>Suzuki, Yusuke</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>20181001</creationdate><title>Effect of Zinc Acetate Dihydrate (NobelzinR) Treatment on Anemia and Taste Disorders in Patients with Chronic Kidney Disease with Hypozincemia</title><author>Sato, Daisuke ; 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The frequency of zinc deficiency in CKD (stages 1-5 and 5D) and CKD improvement via zinc supplementation are not completely verified. Here 500 CKD patients (Stage 1/2, n=100; Stage 3, n=100; Stage 4, n=100, Stage n=5, 100; Stage 5D, n=100) will be recruited to determine the frequency of serum zinc deficiency at each CKD stage. Patients with serum zinc concentrations <80 μg/dL will be treated with zinc acetate dihydrate (NobelzinR) to evaluate its effects on hypozincemia, taste disturbances, and anemia.</abstract><cop>Japan</cop><pmid>30369613</pmid><doi>10.18926/AMO/56254</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Freely Accessible Japanese Titles; Alma/SFX Local Collection |
| subjects | Adult Aged Anemia - drug therapy Cross-Sectional Studies Humans Middle Aged Renal Insufficiency, Chronic - blood Renal Insufficiency, Chronic - complications Taste Disorders - drug therapy Young Adult Zinc - blood Zinc - deficiency Zinc Acetate - therapeutic use |
| title | Effect of Zinc Acetate Dihydrate (NobelzinR) Treatment on Anemia and Taste Disorders in Patients with Chronic Kidney Disease with Hypozincemia |
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