Reversal of Improved Endothelial Function After Bariatric Surgery Is Mitigated by Exercise Training
Inclusion criteria were: age 25 to 55 years, not engaged in any exercise program for at least 1 year before the study, body mass index (BMI) >40 or ≥35 kg/m2 with associated comorbidities, glycosylated hemoglobin (HbA1c)
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| Veröffentlicht in: | Journal of the American College of Cardiology 2018-10, Vol.72 (18), p.2278-2279 |
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| container_title | Journal of the American College of Cardiology |
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| creator | Dantas, Wagner Silva Gil, Saulo Murai, Igor Hisashi Costa-Hong, Valéria Peçanha, Tiago Merege-Filho, Carlos Alberto Abujabra de Sá-Pinto, Ana Lúcia de Cleva, Roberto Santo, Marco Aurélio Pereira, Rosa Maria Rodrigues Kirwan, John P. Roschel, Hamilton Gualano, Bruno |
| description | Inclusion criteria were: age 25 to 55 years, not engaged in any exercise program for at least 1 year before the study, body mass index (BMI) >40 or ≥35 kg/m2 with associated comorbidities, glycosylated hemoglobin (HbA1c) |
| doi_str_mv | 10.1016/j.jacc.2018.07.094 |
| format | Article |
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Brachial FMD (measured following previous recommendations [3]), endothelial-independent dilation, shear rate, surrogates of insulin resistance, lipid profile, blood pressure, body composition (assessed by dual-energy x-ray absorptiometry), aerobic capacity, and anti-inflammatory and proinflammatory cytokines were assessed at baseline and at 3 and 9 months after RYGB surgery. After 3 months, RYGB significantly improved FMD, retrograde shear rate, insulin resistance, cytokines profile, weight, and adiposity (all p < 0.05) (Figure 1), and other cardiometabolic risk factors (e.g., systolic and diastolic blood pressure, lipid profile, HbA1c, endothelial-independent dilation, maximal oxygen consumption; all p < 0.05; data not shown).</description><identifier>ISSN: 0735-1097</identifier><identifier>EISSN: 1558-3597</identifier><identifier>DOI: 10.1016/j.jacc.2018.07.094</identifier><identifier>PMID: 30360835</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adult ; Ankle Brachial Index - trends ; Bariatric Surgery - trends ; Blood Flow Velocity - physiology ; Blood pressure ; Body composition ; Body size ; Brazil - epidemiology ; Cardiology ; Cytokines ; Dilation ; Endothelium, Vascular - physiology ; Exercise ; Exercise - physiology ; Female ; Fitness training programs ; Gangrene ; Gastrointestinal surgery ; Hemoglobin ; Humans ; Insulin ; Insulin resistance ; Lipids ; Middle Aged ; Obesity, Morbid - epidemiology ; Obesity, Morbid - physiopathology ; Obesity, Morbid - surgery ; Oxygen consumption ; Physical fitness ; Risk analysis ; Shear rate ; Shear strength ; Surgery ; Tumor necrosis factor-TNF ; Weight</subject><ispartof>Journal of the American College of Cardiology, 2018-10, Vol.72 (18), p.2278-2279</ispartof><rights>2018 American College of Cardiology Foundation</rights><rights>2018. 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Brachial FMD (measured following previous recommendations [3]), endothelial-independent dilation, shear rate, surrogates of insulin resistance, lipid profile, blood pressure, body composition (assessed by dual-energy x-ray absorptiometry), aerobic capacity, and anti-inflammatory and proinflammatory cytokines were assessed at baseline and at 3 and 9 months after RYGB surgery. After 3 months, RYGB significantly improved FMD, retrograde shear rate, insulin resistance, cytokines profile, weight, and adiposity (all p < 0.05) (Figure 1), and other cardiometabolic risk factors (e.g., systolic and diastolic blood pressure, lipid profile, HbA1c, endothelial-independent dilation, maximal oxygen consumption; all p < 0.05; data not shown).</description><subject>Adult</subject><subject>Ankle Brachial Index - trends</subject><subject>Bariatric Surgery - trends</subject><subject>Blood Flow Velocity - physiology</subject><subject>Blood pressure</subject><subject>Body composition</subject><subject>Body size</subject><subject>Brazil - epidemiology</subject><subject>Cardiology</subject><subject>Cytokines</subject><subject>Dilation</subject><subject>Endothelium, Vascular - physiology</subject><subject>Exercise</subject><subject>Exercise - physiology</subject><subject>Female</subject><subject>Fitness training programs</subject><subject>Gangrene</subject><subject>Gastrointestinal surgery</subject><subject>Hemoglobin</subject><subject>Humans</subject><subject>Insulin</subject><subject>Insulin resistance</subject><subject>Lipids</subject><subject>Middle Aged</subject><subject>Obesity, Morbid - epidemiology</subject><subject>Obesity, Morbid - physiopathology</subject><subject>Obesity, Morbid - surgery</subject><subject>Oxygen consumption</subject><subject>Physical fitness</subject><subject>Risk analysis</subject><subject>Shear rate</subject><subject>Shear strength</subject><subject>Surgery</subject><subject>Tumor necrosis factor-TNF</subject><subject>Weight</subject><issn>0735-1097</issn><issn>1558-3597</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kcFu1DAQhi0EotvCC3BAlrhwSRjHSWxLXNpqW1YqQoJytrz2ZHGUTYrtrNi34Vl4Mhxt4cCB00ij7_818_-EvGJQMmDtu77sjbVlBUyWIEpQ9ROyYk0jC94o8ZSsQPCmYKDEGTmPsQeAVjL1nJxx4C1I3qyI-4wHDNEMdOroZv8QpgM6uh7dlL7h4PP-Zh5t8tNIL7uEgV6Z4E0K3tIvc9hhONJNpB998juTsnJ7pOsfGKyP-OvnfTB-9OPuBXnWmSHiy8d5Qb7erO-vPxR3n24315d3ha0bSAWvutq1KJiCurWmdtxZWXW2scYJNJaD4ghdK1EyrN3WKeC8q5RoRbtFC_yCvD355je-zxiT3vtocRjMiNMcdcWqVrEqh5PRN_-g_TSHMV-3UDUoKZvFsDpRNkwxBuz0Q_B7E46agV460L1eOtBLBxqEzh1k0etH63m7R_dX8if0DLw_AZizOHgMOlqPo0XnA9qk3eT_5_8bx7WYzw</recordid><startdate>20181030</startdate><enddate>20181030</enddate><creator>Dantas, Wagner Silva</creator><creator>Gil, Saulo</creator><creator>Murai, Igor Hisashi</creator><creator>Costa-Hong, Valéria</creator><creator>Peçanha, Tiago</creator><creator>Merege-Filho, Carlos Alberto Abujabra</creator><creator>de Sá-Pinto, Ana Lúcia</creator><creator>de Cleva, Roberto</creator><creator>Santo, Marco Aurélio</creator><creator>Pereira, Rosa Maria Rodrigues</creator><creator>Kirwan, John P.</creator><creator>Roschel, Hamilton</creator><creator>Gualano, Bruno</creator><general>Elsevier Inc</general><general>Elsevier Limited</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7TK</scope><scope>H94</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope></search><sort><creationdate>20181030</creationdate><title>Reversal of Improved Endothelial Function After Bariatric Surgery Is Mitigated by Exercise Training</title><author>Dantas, Wagner Silva ; 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Brachial FMD (measured following previous recommendations [3]), endothelial-independent dilation, shear rate, surrogates of insulin resistance, lipid profile, blood pressure, body composition (assessed by dual-energy x-ray absorptiometry), aerobic capacity, and anti-inflammatory and proinflammatory cytokines were assessed at baseline and at 3 and 9 months after RYGB surgery. After 3 months, RYGB significantly improved FMD, retrograde shear rate, insulin resistance, cytokines profile, weight, and adiposity (all p < 0.05) (Figure 1), and other cardiometabolic risk factors (e.g., systolic and diastolic blood pressure, lipid profile, HbA1c, endothelial-independent dilation, maximal oxygen consumption; all p < 0.05; data not shown).</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>30360835</pmid><doi>10.1016/j.jacc.2018.07.094</doi><tpages>2</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Adult Ankle Brachial Index - trends Bariatric Surgery - trends Blood Flow Velocity - physiology Blood pressure Body composition Body size Brazil - epidemiology Cardiology Cytokines Dilation Endothelium, Vascular - physiology Exercise Exercise - physiology Female Fitness training programs Gangrene Gastrointestinal surgery Hemoglobin Humans Insulin Insulin resistance Lipids Middle Aged Obesity, Morbid - epidemiology Obesity, Morbid - physiopathology Obesity, Morbid - surgery Oxygen consumption Physical fitness Risk analysis Shear rate Shear strength Surgery Tumor necrosis factor-TNF Weight |
| title | Reversal of Improved Endothelial Function After Bariatric Surgery Is Mitigated by Exercise Training |
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