Bifunctional peptide hybrids targeting the matrix of mitochondria

The mitochondrial organelle is associated with many diseases, including diabetes, age-related neuro-degenerative diseases and cancer. Therefore, the effective delivery of drug molecules to mitochondria became increasingly important during the past years. Within this work, we designed and analyzed bi...

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Veröffentlicht in:	Journal of controlled release 2018-12, Vol.291, p.147-156
Hauptverfasser:	Klimpel, Annika, Neundorf, Ines
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell-penetrating peptides Chlorambucil Endosomal release Mitochondrial-targeting Targeted drug delivery
Online-Zugang:	Volltext
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