Metabolite profiling of traditional Chinese medicine formula Dan Zhi Tablet: An integrated strategy based on UPLC-QTOF/MS combined with multivariate statistical analysis

[Display omitted] •An integrated strategy was developed for screening and identifying of constituents from biological samples.•The method of UPLC-QTOF/MS combined with UNIFI software and data-mining technique OPLS-DA was applied.•Comprehensive metabolic profile of DZT was proposed for the first time...

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Veröffentlicht in:	Journal of pharmaceutical and biomedical analysis 2019-02, Vol.164, p.70-85
Hauptverfasser:	Mi, Nan, Cheng, Taofang, Li, Huiliang, Yang, Peiming, Mu, Xuemei, Wang, Xinyu, Zu, Xianpeng, Qi, Xiaopo, Guo, Xin, Ye, Ji, Zhang, Weidong
Format:	Artikel
Sprache:	eng
Schlagworte:	Cerebrospinal fluid Metabolic profile OPLS-DA Rat plasma Traditional Chinese medicine formula Dan Zhi Tablet UPLC-QTOF/MS
Online-Zugang:	Volltext
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