Degradation of Bupropion: Implications for Interpretation of Postmortem Case Data

The interpretation of postmortem bupropion is often a challenge to the forensic toxicology community because of the instability of the parent compound. At the North Carolina Office of the Chief Medical Examiner (NC OCME) toxicology laboratory, one of the active metabolites, threobupropion, is used a...

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Veröffentlicht in:	Journal of analytical toxicology 2018-10, Vol.42 (8), p.525-536
Hauptverfasser:	Bishop-Freeman, Sandra C, Hensel, Erin M, Feaster, Marc S, Winecker, Ruth E
Format:	Artikel
Sprache:	eng
Schlagworte:	Antidepressive Agents, Second-Generation - analysis Antidepressive Agents, Second-Generation - blood Bupropion - analysis Bupropion - blood Forensic Toxicology - methods Gas Chromatography-Mass Spectrometry Humans Limit of Detection Liquid-Liquid Extraction Liver - chemistry Liver - pathology Postmortem Changes Reproducibility of Results
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