Prolonged exposure to tenofovir monotherapy 1 month after treatment discontinuation because of tenofovir-related renal failure

In this study, we present a case of renal failure in a patient who was on a tenofovir-containing regimen, resulting in extremely high tenofovir exposure and prolonged tenofovir monotherapy. We considered this case report important because exposure to tenofovir monotherapy might have consequences for...

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Veröffentlicht in:Antiviral therapy 2009-01, Vol.14 (2), p.299-301
Hauptverfasser: TER HEINE, Rob, HUITEMA, Alwin D. R, JANSEN, Robert S, SMITS, Paul H. M, VAN GORP, Eric C. M, WAGENAAR, Jiri F. P, BEIJNEN, Jos H, MULDER, Jan W
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Sprache:eng
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Zusammenfassung:In this study, we present a case of renal failure in a patient who was on a tenofovir-containing regimen, resulting in extremely high tenofovir exposure and prolonged tenofovir monotherapy. We considered this case report important because exposure to tenofovir monotherapy might have consequences for future discontinuation strategies in cases of renal failure.
ISSN:1359-6535
2040-2058
DOI:10.1177/135965350901400202