Pulmonary toxicities of biologies: a review

Pulmonary toxicities of biologies: a review

With the advancement of research in cancer treatment more and more drugs are being introduced for the treatment of cancer. In this review study, we have tried to look at some of the relatively newly introduced drugs, commonly referred to as biologies. The aim of this study was to review the very rar...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Anti-cancer drugs 2010-02, Vol.21 (2), p.131-139
Hauptverfasser: Peerzada, M M, Spiro, T P, Daw, HA
Format: Artikel
Sprache:eng
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 139
container_issue 2
container_start_page 131
container_title Anti-cancer drugs
container_volume 21
creator Peerzada, M M
Spiro, T P
Daw, HA
description With the advancement of research in cancer treatment more and more drugs are being introduced for the treatment of cancer. In this review study, we have tried to look at some of the relatively newly introduced drugs, commonly referred to as biologies. The aim of this study was to review the very rare but fatal pulmonary toxicities (mostly interstitial lung disease) caused by these drugs. The drugs that were reviewed are rituximab, cetuximab, bevacizumab, alemtuzumab, and trastuzumab. This review basically aims at presenting a basic introduction (mechanism of action and indications of use) of these drugs followed by a summary of the incidence, various clinical presentations, diagnosis, treatment options, and outcome of patients around the world who presented with pulmonary toxicities caused by these drugs.
doi_str_mv 10.1097/CAD.0b013e328333d662
format Article
fullrecord <record><control><sourceid>proquest</sourceid><recordid>TN_cdi_proquest_miscellaneous_21261363</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>21261363</sourcerecordid><originalsourceid>FETCH-proquest_miscellaneous_212613633</originalsourceid><addsrcrecordid>eNqNyrsOgjAUgOEOmoiXN3Do5GLAtgeLdTOocXRwJwUPpqZQpeDl7XXwAZz-fMlPyJSziDOVLNLNNmI544AgVgBwllL0SMDUUoWxSmBAht5fGWNJzCEg82NnK1fr5k1b9zKFaQ166kqaG2fd5Ys11bTBh8HnmPRLbT1Ofh2R2X53Sg_hrXH3Dn2bVcYXaK2u0XU-E1xIDhLg7_EDBN86dg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>21261363</pqid></control><display><type>article</type><title>Pulmonary toxicities of biologies: a review</title><source>Journals@Ovid Complete</source><creator>Peerzada, M M ; Spiro, T P ; Daw, HA</creator><creatorcontrib>Peerzada, M M ; Spiro, T P ; Daw, HA</creatorcontrib><description>With the advancement of research in cancer treatment more and more drugs are being introduced for the treatment of cancer. In this review study, we have tried to look at some of the relatively newly introduced drugs, commonly referred to as biologies. The aim of this study was to review the very rare but fatal pulmonary toxicities (mostly interstitial lung disease) caused by these drugs. The drugs that were reviewed are rituximab, cetuximab, bevacizumab, alemtuzumab, and trastuzumab. This review basically aims at presenting a basic introduction (mechanism of action and indications of use) of these drugs followed by a summary of the incidence, various clinical presentations, diagnosis, treatment options, and outcome of patients around the world who presented with pulmonary toxicities caused by these drugs.</description><identifier>ISSN: 0959-4973</identifier><identifier>DOI: 10.1097/CAD.0b013e328333d662</identifier><language>eng</language><ispartof>Anti-cancer drugs, 2010-02, Vol.21 (2), p.131-139</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids></links><search><creatorcontrib>Peerzada, M M</creatorcontrib><creatorcontrib>Spiro, T P</creatorcontrib><creatorcontrib>Daw, HA</creatorcontrib><title>Pulmonary toxicities of biologies: a review</title><title>Anti-cancer drugs</title><description>With the advancement of research in cancer treatment more and more drugs are being introduced for the treatment of cancer. In this review study, we have tried to look at some of the relatively newly introduced drugs, commonly referred to as biologies. The aim of this study was to review the very rare but fatal pulmonary toxicities (mostly interstitial lung disease) caused by these drugs. The drugs that were reviewed are rituximab, cetuximab, bevacizumab, alemtuzumab, and trastuzumab. This review basically aims at presenting a basic introduction (mechanism of action and indications of use) of these drugs followed by a summary of the incidence, various clinical presentations, diagnosis, treatment options, and outcome of patients around the world who presented with pulmonary toxicities caused by these drugs.</description><issn>0959-4973</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><recordid>eNqNyrsOgjAUgOEOmoiXN3Do5GLAtgeLdTOocXRwJwUPpqZQpeDl7XXwAZz-fMlPyJSziDOVLNLNNmI544AgVgBwllL0SMDUUoWxSmBAht5fGWNJzCEg82NnK1fr5k1b9zKFaQ166kqaG2fd5Ys11bTBh8HnmPRLbT1Ofh2R2X53Sg_hrXH3Dn2bVcYXaK2u0XU-E1xIDhLg7_EDBN86dg</recordid><startdate>20100201</startdate><enddate>20100201</enddate><creator>Peerzada, M M</creator><creator>Spiro, T P</creator><creator>Daw, HA</creator><scope>7U7</scope><scope>C1K</scope></search><sort><creationdate>20100201</creationdate><title>Pulmonary toxicities of biologies: a review</title><author>Peerzada, M M ; Spiro, T P ; Daw, HA</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-proquest_miscellaneous_212613633</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Peerzada, M M</creatorcontrib><creatorcontrib>Spiro, T P</creatorcontrib><creatorcontrib>Daw, HA</creatorcontrib><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><jtitle>Anti-cancer drugs</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Peerzada, M M</au><au>Spiro, T P</au><au>Daw, HA</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pulmonary toxicities of biologies: a review</atitle><jtitle>Anti-cancer drugs</jtitle><date>2010-02-01</date><risdate>2010</risdate><volume>21</volume><issue>2</issue><spage>131</spage><epage>139</epage><pages>131-139</pages><issn>0959-4973</issn><abstract>With the advancement of research in cancer treatment more and more drugs are being introduced for the treatment of cancer. In this review study, we have tried to look at some of the relatively newly introduced drugs, commonly referred to as biologies. The aim of this study was to review the very rare but fatal pulmonary toxicities (mostly interstitial lung disease) caused by these drugs. The drugs that were reviewed are rituximab, cetuximab, bevacizumab, alemtuzumab, and trastuzumab. This review basically aims at presenting a basic introduction (mechanism of action and indications of use) of these drugs followed by a summary of the incidence, various clinical presentations, diagnosis, treatment options, and outcome of patients around the world who presented with pulmonary toxicities caused by these drugs.</abstract><doi>10.1097/CAD.0b013e328333d662</doi></addata></record>
fulltext fulltext
identifier ISSN: 0959-4973
ispartof Anti-cancer drugs, 2010-02, Vol.21 (2), p.131-139
issn 0959-4973
language eng
recordid cdi_proquest_miscellaneous_21261363
source Journals@Ovid Complete
title Pulmonary toxicities of biologies: a review
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-25T11%3A16%3A37IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Pulmonary%20toxicities%20of%20biologies:%20a%20review&rft.jtitle=Anti-cancer%20drugs&rft.au=Peerzada,%20M%20M&rft.date=2010-02-01&rft.volume=21&rft.issue=2&rft.spage=131&rft.epage=139&rft.pages=131-139&rft.issn=0959-4973&rft_id=info:doi/10.1097/CAD.0b013e328333d662&rft_dat=%3Cproquest%3E21261363%3C/proquest%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=21261363&rft_id=info:pmid/&rfr_iscdi=true