Absence of Myocardial Fibrosis Predicts Favorable Long-Term Survival in New-Onset Heart Failure

Myocardial fibrosis, identified by late gadolinium enhancement cardiovascular magnetic resonance, predicts outcomes in chronic heart failure (HF). Its prognostic significance in new-onset HF and reduced left ventricular ejection fraction (LVEF) is unclear. We investigated whether the pattern and ext...

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Veröffentlicht in:	Circulation. Cardiovascular imaging 2018-09, Vol.11 (9), p.e007722-e007722
Hauptverfasser:	Gulati, Ankur, Japp, Alan G, Raza, Sadaf, Halliday, Brian P, Jones, Daniel A, Newsome, Simon, Ismail, Nizar A, Morarji, Kishen, Khwaja, Jahanzaib, Spath, Nick, Shakespeare, Carl, Kalra, Paul R, Lloyd, Guy, Mathur, Anthony, Cleland, John G F, Cowie, Martin R, Assomull, Ravi G, Pennell, Dudley J, Ismail, Tevfik F, Prasad, Sanjay K
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Cause of Death Female Fibrosis Heart Failure - diagnostic imaging Heart Failure - pathology Heart Failure - physiopathology Heart Failure - therapy Humans Magnetic Resonance Imaging, Cine Male Middle Aged Myocardium - pathology Predictive Value of Tests Prognosis Prospective Studies Risk Assessment Risk Factors Stroke Volume Time Factors Ventricular Function, Left Ventricular Remodeling
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Zusammenfassung:	Myocardial fibrosis, identified by late gadolinium enhancement cardiovascular magnetic resonance, predicts outcomes in chronic heart failure (HF). Its prognostic significance in new-onset HF and reduced left ventricular ejection fraction (LVEF) is unclear. We investigated whether the pattern and extent of fibrosis predict survival in new-onset HF and reduced LVEF of initially uncertain pathogenesis. Of 120 consecutive patients with new-onset (
ISSN:	1942-0080
DOI:	10.1161/circimaging.118.007722