Anti-α4β7 integrin monoclonal antibody (vedolizumab) for the treatment of steroid-resistant severe intestinal acute graft-versus-host disease

Steroid-resistant (SR) acute graft-versus-host disease (aGvHD) is a life-threatening complication of allogeneic stem cell transplantation. Vedolizumab is a monoclonal antibody that impairs homing of T cells to the gastrointestinal (GI) endothelium by blocking the α4β7 integrin. We retrospectively an...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Bone marrow transplantation (Basingstoke) 2019-07, Vol.54 (7), p.987-993
Hauptverfasser:	Danylesko, Ivetta, Bukauskas, Adomas, Paulson, Martin, Peceliunas, Valdas, Gedde-Dahl d.y, Tobias, Shimoni, Avichai, Shouval, Roni, Griskevicius, Laimonas, Floisand, Yngvar, Nagler, Arnon
Format:	Artikel
Sprache:	eng
Schlagworte:	13/1 13/100 692/699/249/1529 692/700/565/1436/2185 Cell Biology Clinical trials Complications Endothelium Graft-versus-host reaction Hematology Histopathology Homing Immunosuppression Internal Medicine Intestine Lymphocytes Lymphocytes T Medical research Medical treatment Medicine Medicine & Public Health Monoclonal antibodies Patients Public Health Stem cell transplantation Stem Cells Steroids Transplantation
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!