Weekly Irinotecan Plus Protracted Venous Fluorouracil Infusion (WI-FI) in Advanced Colorectal Cancer: A Phase II Study

Background: Irinotecan (IRI) is a topoisomerase I inhibitor active as first- or second-line chemotherapy in advanced colorectal cancer (ACRC). Its combination with fluorouracil (FU) increases the response rate and prolongs survival. In order to identify a new effective and less toxic schedule of adm...

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Veröffentlicht in:	Anticancer research 2008-07, Vol.28 (4C), p.2327-2332
Hauptverfasser:	OLIVA, Cristiano, POCHETTINO, Paolo, COMANDONE, Alessandro, BERGNOLO, Paola, BOGLIONE, Antonella, CHIADO CUTIN, Simona, INGUI, Manuela, DAL CANTON, Orietta, GARETTO, Ferdinando, BISCARDI, Manuela, BERNO, Elisa
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - drug therapy Adolescent Adult Aged Antineoplastic Combined Chemotherapy Protocols - administration & dosage Antineoplastic Combined Chemotherapy Protocols - adverse effects Biological and medical sciences Camptothecin - administration & dosage Camptothecin - adverse effects Camptothecin - analogs & derivatives Catheterization, Central Venous Colorectal Neoplasms - drug therapy Drug Administration Schedule Female Fluorouracil - administration & dosage Fluorouracil - adverse effects Gastroenterology. Liver. Pancreas. Abdomen Humans Infusions, Intravenous Male Medical sciences Middle Aged Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Tumors
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