An Invariant Arginine in Common with MHC Class II Allows Extension at the C-Terminal End of Peptides Bound to Chicken MHC Class I

MHC molecules are found in all jawed vertebrates and are known to present peptides to T lymphocytes. In mammals, peptides can hang out either end of the peptide-binding groove of classical class II molecules, whereas the N and C termini of peptides are typically tightly bound to specific pockets in...

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Veröffentlicht in:	The Journal of immunology (1950) 2018-11, Vol.201 (10), p.3084-3095
Hauptverfasser:	Xiao, Jin, Xiang, Wangzhen, Zhang, Yongli, Peng, Weiyu, Zhao, Min, Niu, Ling, Chai, Yan, Qi, Jianxun, Wang, Fei, Qi, Peng, Pan, Chungang, Han, Lingxia, Wang, Ming, Kaufman, Jim, Gao, George F, Liu, William J
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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